Immune response
Gene:
PASD1 (official gene symbol)Other symbol:
PASD1CT family:
CT63CT identifier:
CT63Humoral immune response
PASD1 was identified by SEREX (Guinn et al., 2005).
Spontaneous humoral immune responses against PASD1 were detected in cancer patients.
Tumor type | Tumor stage | Frequency | Antibody detection methodology | PMID |
---|---|---|---|---|
Cervical carcinoma | 1/31 (3%) | ELISA | 19540335 | |
Lung carcinoma | 0/19 (0%) | ELISA | 19540335 | |
Colon carcinoma | 0/18 (0%) | ELISA | 19540335 | |
Glioblastoma | 2/25 (8%) | ELISA | 19540335 |
Cellular immune response
CTL response, as well as CD4-positive T-helper response to PASD1 were observed in diffuse large B-cell lymphoma patients (Ait-Tahar et al., 2009 PMID: 19552722; Ait-Tahar et al, 2010 PMID: 20851862).
Induced immune response
There are no published reports that evaluated induced immune responses in patients vaccinated with PASD1.