Summary
Gene:
JARID1B (official gene symbol)Other symbol:
JARID1BCT family:
CT31CT identifier:
CT31Aliases from NCBI:
FLJ10538 , FLJ12459 , FLJ12491 , FLJ16281 , FLJ23670 , KDM5B , PLU-1 , PUT1 , RBBP2H1A
JARID1B is located at 1q32.1.
JARID1B has been reported to be expressed in myeloma and breast cancer at the mRNA level and at prostate and breast cancers at the protein level. JARID1B is expressed in benign melanocytic lesions, but not in melanomas at the mRNA and protein levels.
JARID1 is a member of the histone demethylase family and acts as a strong transcriptional repressor.