Immune response
Gene:
ROPN1 (official gene symbol)Other symbol:
ROPN1CT family:
CT91CT identifier:
CT91Aliases from NCBI:
DKFZp434B1222 , ODF6 , RHPNAP1 , ROPN1A , ropporinHumoral immune response
Gene expression in in hematologic malignancies is associated with the presence of high titer IgG antibodies against ROPN1.
| Tumor type | Tumor stage | Frequency | Antibody detection methodology | PMID |
|---|---|---|---|---|
| Myeloma | 8/30 (27%) | ELISA | 17551920 | |
| Chronic lymphocytic leukemia | 18/31 (58%) | ELISA | 17551920 | |
| Acute myeloid leukemia | 7/24 (29%) | ELISA | 17551920 | |
| Chronic myeloid leukemia | 9/27 (33%) | ELISA | 17551920 | |
| Acute lymphocytic leukemia | 1/3 (33%) | ELISA | 17551920 |
Cellular immune response
There are no published reports of spontaneous cellular immune responses against ROPN1 in cancer patients.
Induced immune response
There are no published reports that evaluated induced immune responses in patients vaccinated with ROPN1.