Immune response
Gene:
CSAG2 (official gene symbol)Other symbol:
CSAG2CT family:
CT24CT identifier:
CT24.2Aliases from NCBI:
MGC149851 , MGC149852 , TRAG3Unified entry for genes CSAG2, CSAG3B (nearly-identical copies)
Humoral immune response
There are no published reports of humoral immune responses against CSAG2 in cancer patients.
Cellular immune response
Spontaneous cellular immune responses against CSAG2 in cancer patients were detected by Meier et al., 2005; Janjic et al., 2006 .
The following CSAG2 epitopes recognized by T cells have been identified after stimulation of lymphocytes in vitro.
| HLA | HLA Frequency (%) | Peptide | Position | Lymphocyte Stimulation Method |
PMID |
|---|---|---|---|---|---|
| DR1 | 18 | CEFHACWPAFTVLGE | 34-48 | peptide | 16888034 |
| DR4 | 24 | CEFHACWPAFTVLGE | 34-48 | peptide | 16888034 |
| DR7 | 25 | CEFHACWPAFTVLGE | 34-48 | peptide | 16888034 |
Induced immune response
There are no published reports that evaluated induced immune responses in patients vaccinated with CSAG2.