Protein
Gene:
TMEFF1 (official gene symbol)Other symbol:
TMEFF1CT family:
CT 120CT identifier:
CT 120.1RefSeq :
Cellular localization
Subcellular Localization | Cell type | Methodology | PMID |
---|---|---|---|
cell membrane | U118 brain cell line | Indirect immunofluorescence | 12743596 |
Protein function and interaction
Tomoregulin-1 is a transmembrane protein that modulates signals through different TGF-b ligands during vertebrate development. TMEFF1 acts as a nodal inhibitor, binding directly to the nodal coreceptor Cripto in Xenopus embryos (Harms et al., 2003 PMID: 14563676).