Protein

Gene:

ADAM29 (official gene symbol)

Other symbol:

ADAM29

CT family:

CT73

CT identifier:

CT73

Aliases from NCBI:

svph1

RefSeq :

NP_055084.3

Protein Names (UNIPROT)

ADAM 29 precursor

Cellular localization

Unknown.

Protein function and interaction

ADAM29 contains all the domains of a typical ADAM molecule, including a signal peptide, a proprotein domain, a metalloprotease domain, a disintegrin domain, a cysteine-rich domain, a transmembrane region, and a cytoplasmic tail. Within the cysteine-rich domain, a short hydrophobic stretch can be modeled into an amphipathic helix with a central proline residue, a characteristic of the putative fusion peptide identified in the membrane-anchored subunit, suggesting that ADAM29 may play a role in mediating cell–cell fusion (Xu et al., 1999 PMID: 10644455).