Protein
Gene:
OIP5 (official gene symbol)Other symbol:
OIP5CT family:
CT86CT identifier:
CT86Aliases from NCBI:
5730547N13Rik , LINT-25 , MIS18betaRefSeq :
NP_009211.1 
Protein Names (UNIPROT)
Opa-interacting protein 5
Cellular localization
Subcellular Localization | Cell type | Methodology | PMID |
---|---|---|---|
nucleus | HeLA cell line | Western blot | 17284516 |
Protein function and interaction
OIP5 binds the outer membrane protein OpaP from Neisseria gonorrhoeae (Williams et al., 1998 PMID: 9466265).
OIP5 is a potential binding partner of Lamina-associated polypeptide 2 alpha (LAP2a). LINT-25 (0IP5) is upregulated during G1 phase of cell proliferation and upon cell cycle exit during quiescence, senescence and differentiation. The upregulation of LINT-25 is accompanied by its translocation into heterochromatin foci, also called chromocenters, which may be involved in chromatin reorganization during cell cycle exit (Naetar et al., 2007 PMID: 17284516).