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List of genes:

Protein

Gene: 

OIP5 (official gene symbol)

Other symbol: 

OIP5

CT family: 

CT86 

CT identifier: 

CT86

Aliases from NCBI:

5730547N13Rik , LINT-25 , MIS18beta

RefSeq :

NP_009211.1 

Protein Names (UNIPROT)

Opa-interacting protein 5

Cellular localization

Subcellular Localization Cell type Methodology PMID
nucleus HeLA cell line Western blot 17284516

Protein function and interaction

OIP5 binds the outer membrane protein OpaP from Neisseria gonorrhoeae (Williams et al., 1998 PMID: 9466265).

OIP5 is a potential binding partner of Lamina-associated polypeptide 2 alpha (LAP2a). LINT-25 (0IP5) is upregulated during G1 phase of cell proliferation and upon cell cycle exit during quiescence, senescence and differentiation. The upregulation of LINT-25 is accompanied by its translocation into heterochromatin foci, also called chromocenters, which may be involved in chromatin reorganization during cell cycle exit (Naetar et al., 2007 PMID: 17284516).

Domain analysis