| 1 | 07/01/2004 | 15220211 | Genome-wide linkage analysis for severe obesity in french caucasians finds significant susceptibility locus on chromosome 19q. |  | 
 
                  |  | To ascertain whether distinct chromosomal loci existed that were linked to severe obesity, as well as to utilize the increased heritability of this excessive phenotype, we performed a genome-wide scan... 
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                  | 2 | 01/01/2004 | 14708010 | Tubby proteins: the plot thickens. |  | 
 
                  |  | The tubby mouse, which shows late-onset obesity and neurosensory deficits, arises from a mutation in the Tub gene. Tub shares homology with the genes for tubby-like proteins Tulp1, Tulp2 and Tulp3. Ab... 
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                  | 3 | 07/25/2001 | 11483369 | Molecular cloning, expression and regulation of the avian tubby-like protein 1 (tulp1) gene. |  | 
 
                  |  | The tubby-like protein 1 (tulp1) gene is a member of the tubby multigene family which includes tub, tulp1, tulp2 and tulp3. Human and mouse tulp1 genes were cloned and mutations in tulp1 have been imp... 
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                  | 4 | 09/30/2000 | 11000483 | GFP-tagged expression and immunohistochemical studies to determine the subcellular localization of the tubby gene family members. |  | 
 
                  |  | The tubby gene family consists of four members, TUB, TULP1, TULP2 and TULP3, with unknown function. However, a splice junction mutation within the mouse tub gene leads to retinal and cochlear degenera... 
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                  | 5 | 12/01/1998 | 9828123 | Molecular characterization of a novel tubby gene family member, TULP3, in mouse and humans. |  | 
 
                  |  | Tubby and related proteins are derived from a small family of novel genes. The carboxytermini of this family are highly conserved across a number of species including humans, mice, Caenorhabditis eleg... 
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                  | 6 | 04/01/1997 | 9096357 | Molecular characterization of TUB, TULP1, and TULP2, members of the novel tubby gene family and their possible relation to ocular diseases. |  | 
 
                  |  | Tubby, an autosomal recessive mutation, mapping to mouse chromosome 7, was recently found to be the result of a splicing defect in a novel gene with unknown function. Database searches revealed that s... 
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