1 |
12/01/2007 |
18062861 |
Gene polymorphisms and male infertility - a meta-analysis and literature review. |
|
|
Many genetic polymorphisms have been studied extensively to elucidate their role in the pathophysiology of male infertility. This article presents a review of the literature following a thorough searc...
|
2 |
11/01/2007 |
17851739 |
Contiguous X-chromosome Deletion Syndrome Encompassing the BTK, TIMM8A, TAF7L, and DRP2 Genes. |
|
|
X-linked agammaglobulinemia (XLA) is characterized by low levels of B-lymphocytes with early-onset, recurrent, microbial infections occasionally causing neurological symptoms. We observed an atypical ...
|
3 |
10/01/2007 |
17714218 |
Mutation analysis of the X-chromosome linked, testis-specific TAF7L gene in spermatogenic failure. |
|
|
The precise temporal and spatial expressions of specific transcription regulation factors (TRF) have long been considered essential for spermatogenesis. Recently, it has been speculated that mammals h...
|
4 |
04/01/2007 |
17242199 |
Abnormal sperm in mice lacking the Taf7l gene. |
|
|
TFIID is a general transcription factor required for transcription of most protein-coding genes by RNA polymerase II. TAF7L is an X-linked germ cell-specific paralogue of TAF7, which is a generally ex...
|
5 |
04/01/2006 |
16597641 |
The role of the testis-specific gene hTAF7L in the aetiology of male infertility. |
|
|
The X-linked TAF7L gene is homologous to the autosomal transcription factor TAF7. Together with its testis-specific expression pattern, this might point to an important function in spermatogenesis. In...
|
6 |
07/01/2004 |
15232059 |
Testis-specific transcription mechanisms promoting male germ-cell differentiation. |
|
|
Male germ-cell differentiation requires spermatogenic stage- and cell-specific gene expression that is achieved by unique chromatin remodeling, transcriptional control and the expression of testis-spe...
|
7 |
06/20/2003 |
12704671 |
Five new human cancer-germline genes identified among 12 genes expressed in spermatogonia. |
|
|
An important class of tumor-specific antigens is encoded by male germline-specific genes, such as MAGE genes, that are activated in many cancers of various histological types as a result of the demeth...
|
8 |
05/01/2003 |
12665565 |
The intracellular localisation of TAF7L, a paralogue of transcription factor TFIID subunit TAF7, is developmentally regulated during male germ-cell differentiation. |
|
|
Transcription regulation in male germ cells can involve specialised mechanisms and testis-specific paralogues of the general transcription machinery. Here we describe TAF7L, a germ-cell-specific paral...
|