Immune response
Gene:
MPHOSPH1 (official gene symbol)Other symbol:
MPHOSPH1CT family:
CT90CT identifier:
CT90Aliases from NCBI:
DKFZp434B0435 , DKFZp434P0810 , KRMP1 , MPP-1 , MPP1Humoral immune response
There are no published reports of spontaneous humoral immune responses against MPHOSPH1 in cancer patients. However, MPHOSPH1 (MPP1) was reported to be a target autoantigen in patients with idiopathic ataxia (Fritzler et al., 2000 PMID: 10695267).
Cellular immune response
MPHOSPH1-278 vaccine is well tolerated by advanced bladder cancer patients and induce peptide-specific CTLs in vivo (Obara et al., 2012 PMID:22636067).