Immune response
Gene:
BAGE (official gene symbol)Other symbol:
BAGECT family:
CT2CT identifier:
CT2.1Aliases from NCBI:
BAGE1Unified entry for BAGE, BAGE2, BAGE3, BAGE4, BAGE5
Humoral immune response
There are no published reports of spontaneous humoral immune responses against BAGE in cancer patients.
Cellular immune response
BAGE was identified by its ability to be recognized by CTLs and may elicit spontaneous cellular immune responses in cancer patients (Böel et al., 1995).
The following BAGE epitope recognized T cells has been identified after stimulation of lymphocytes in vitro (Cancer Immunity Peptide Database).
HLA | HLA Frequency (%) | Peptide | Position | Lymphocyte Stimulation Method |
PMID |
---|---|---|---|---|---|
Cw16 | 7 | AARAVFLAL | 2-10 | autologous tumor cells | 7895173 |
Induced immune response
There are no published reports that evaluated induced immune responses in patients vaccinated with BAGE.