Immune response
Gene:
PLAC1 (official gene symbol)Other symbol:
PLAC1CT family:
CT92CT identifier:
CT92Humoral immune response
Spontaneous humoral immune responses against PLAC1 have been detected in cancer patients.
| Tumor type | Tumor stage | Frequency | Antibody detection methodology | PMID |
|---|---|---|---|---|
| Gastrict carcinoma | 8/28(29%) | ELISA | 16617350 | |
| Hepatocellular carcinoma | 4/101 (4%) | 18183594 | ||
| Adenocarcinoma of the large intestine | 2.6% | ELISA | 23390371 |
Cellular immune response
HLA-A2-restricted cytotoxic T lymphocyte epitopes derived from PLAC1 were identified in breast cancer (Liu et al., 2011 PMID: 21710262).
Induced immune response
There are no published reports that evaluated induced immune responses in patients vaccinated with PLAC1.