Immune response
Gene:
ACRBP (official gene symbol)Other symbol:
ACRBPCT family:
CT23CT identifier:
CT23Aliases from NCBI:
OY-TES-1 , SP32Humoral immune response
Spontaneous humoral immune responses against ACRBP have been observed in cancer patients.
| Tumor type | Tumor stage | Frequency | Antibody detection methodology | PMID |
|---|---|---|---|---|
| Ovarian cancer | 1/10 (10%) | ELISA | 16964386 | |
| Bladder cancer | 3/58 (5%) | ELISA | 11248070 | |
| Liver cancer | 10/95 (10%) | ELISA | 11248070 | |
| Colon cancer | 6/58 (10%) | ELISA | 11248070 | |
| Prostate cancer | 3/85 (3%) | ELISA | 11248070 | |
| Lung cancer | 3/66(4%) | ELISA | 11248070 |
Cellular immune response
The HLA-A24-binding OY-TES-1 peptide, TES(401-409) was recognized by CD8 T- after stimulation of lymphocytes in vitro (Okumura et al., 2005 PMID: 16301813).
Induced immune response
There are no published reports that evaluated induced immune responses in patients vaccinated with ACRBP.