Protein expression
Gene:
IGF2BP3 (official gene symbol)Other symbol:
IMP-3CT family:
CT98CT identifier:
CT98Published data of protein expression in normal tissues
Show| Tissue | Methodology | PMID | 
|---|---|---|
| Endometrium (gestational) | IHC | 18223334 | 
| Trophoblasts | IHC | 18223334 | 
| Colon | IHC | 12644826 | 
| Fallopian tube | IHC | 12644826 | 
| Ovary | IHC | 12644826 | 
| Pituitary | IHC | 12644826 | 
| Placenta | IHC | 12644826 | 
| Bronchus | IHC | 12644826 | 
| Tonsil | IHC | 12644826 | 
| Placenta | Western blot | 12644826 | 
Published data of protein expression in neoplasias
Hematologic malignacies Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID | 
|---|---|---|---|---|
| Anaplastic large cell lymphoma | 
 6/8 (75%) | IHC | 17296566 | |
| Burkitt lymphoma | 
 2/2 (100%) | IHC | ||
| Diffuse large B-cell lymphoma | 
 155/200 (77%) | IHC | ||
| Follicular lymphoma | 
 126/165 (76%) | IHC | ||
| Hodgkin's lymphoma | 
 101/108 (93%) | IHC | ||
| Lymphocyte-predominant Hodgkin's lymphoma | 
 12/13 (92%) | IHC | ||
| Mediastinal large B-cell lymphoma | 
 9/10 (90%) | IHC | 
Bladder cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID | 
|---|---|---|---|---|
| Invasive urothelial carcinoma | 
 26/44 (59%) | IHC | 18547613 | |
| Non neoplastic urothelium | 
 3/69 (4%) | IHC | ||
| Noninvasive high-grade papillary urothelial carcinoma (PUC-H) | 
 9/17 (53%) | IHC | ||
| Urothelial carcinoma in situ | 
 14/29 (48%) | IHC | ||
| Urothelial carcinoma | 
 Metastatic tumor | 26/28 (93%) | IHC | 18347170 | 
| Urothelial carcinoma | 
 Primary tumor | 42/ 214 (20%) | IHC | 
Esophageal cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID | 
|---|---|---|---|---|
| Squamous cell carcinoma | 
 18/20 (90%) | IHC | 18452554 | |
| Squamous cell carcinoma | 
 9/10 (90%) | IHC | 19459850 | 
Gynecological cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID | 
|---|---|---|---|---|
| Endometrial carcinosarcoma | 
 3/5 (60%) | IHC | 18223334 | |
| Endometrial clear cell carcinoma | 
 9/18 (50%) | IHC | ||
| Endometrial mucinous carcinoma | 
 0/8 (0%) | IHC | ||
| Endometrial serous carcinoma | 
 49/51 (94%) | IHC | ||
| Endometrioid carcinoma | 
 2/70 (3%) | IHC | ||
| Cervical adenocarcinoma in situ | 
 41/44 (93%) | IHC | 17192788 | |
| Endometrial serous carcinoma | 
 45/45 (100%) | IHC | 17885673 | |
| Endometrioid carcinoma | 
 68/122 (56%) | IHC | 
Hepatobiliary cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID | 
|---|---|---|---|---|
| Hepatocellular carcinoma | 
 255/377 (68%) | IHC | 18802962 | 
Kidney cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID | 
|---|---|---|---|---|
| Chromophobe renal cell carcinoma | 
 4/26 (15%) | IHC | 16814207 | |
| Clear-cell renal cell carcinoma | 
 58/252 (23%) | IHC | ||
| Papillary renal cell carcinoma | 
 7/30 (11%) | IHC | ||
| Unclassified renal cell carcinoma | 
 2/2 (100%) | IHC | ||
| Clear-cell renal cell carcinoma | 
 213/716 (30%) | IHC | 18260086 | 
Lung cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID | 
|---|---|---|---|---|
| Adenocarcinoma | 
 12/14 (86%) | IHC | 12644826 | |
| Squamous cell carcinoma | 
 11/12 (92%) | IHC | ||
| Atypical carcinoid | 
 0/21 (0%) | IHC | 17316760 | |
| Large cell neuroendocrine carcinomas (LCNEC) | 
 9/14 (64%) | IHC | ||
| Small cell lung carcinoma | 
 10/10 (100%) | IHC | 
OTHER CANCER Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID | 
|---|---|---|---|---|
| Merkel cell carcinoma | 
 18/20 (90%) | IHC | 18835627 | |
| Mesothelioma | 
 10/11 (91%) | IHC | 18098206 | |
| Extrapulmonary carcinoid tumor | 
 0/22 (0%) | IHC | 17521698 | |
| Extrapulmonary small cell carcinoma | 
 47/53 (89%) | IHC | 
Pancreatic cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID | 
|---|---|---|---|---|
| Ductal carcinoma | 
 25/26 (96%) | IHC | 15644775 | |
| Invasive mucinous cystadenocarcinoma | 
 2/2 (100%) | IHC | ||
| Papillary-mucinous carcinoma | 
 10/10 (100%) | IHC | ||
| Adenocarcinoma | 
 11/12 (92%) | IHC | 18499984 | |
| Adenocarcinoma | 
 35/40 (88%) | IHC | 17924416 | 
Testicular cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID | 
|---|---|---|---|---|
| Carcinoma "in situ" | 
 8/9 (89%) | IHC | 16049158 | |
| Embryonal carcinoma | 
 7/7(100%) | IHC | ||
| Leydig cell tumor | 
 1/2 (50%) | IHC | ||
| Seminoma | 
 3/5 (60%) | IHC | ||
| Spermatocytic seminoma | 
 1/1 (100%) | IHC | ||
| Teratoma | 
 8/8 (100%) | IHC | 
Available antibodies
anti IMP3 (L523S) monoclonal antibody Corixa Corporation (Seattle, WA)
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