Protein expression
Gene:
IGF2BP3 (official gene symbol)Other symbol:
IMP-3CT family:
CT98CT identifier:
CT98Published data of protein expression in normal tissues
Show| Tissue | Methodology | PMID |
|---|---|---|
| Endometrium (gestational) | IHC | 18223334 |
| Trophoblasts | IHC | 18223334 |
| Colon | IHC | 12644826 |
| Fallopian tube | IHC | 12644826 |
| Ovary | IHC | 12644826 |
| Pituitary | IHC | 12644826 |
| Placenta | IHC | 12644826 |
| Bronchus | IHC | 12644826 |
| Tonsil | IHC | 12644826 |
| Placenta | Western blot | 12644826 |
Published data of protein expression in neoplasias
Hematologic malignacies Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Anaplastic large cell lymphoma |
6/8 (75%) | IHC | 17296566 | |
| Burkitt lymphoma |
2/2 (100%) | IHC | ||
| Diffuse large B-cell lymphoma |
155/200 (77%) | IHC | ||
| Follicular lymphoma |
126/165 (76%) | IHC | ||
| Hodgkin's lymphoma |
101/108 (93%) | IHC | ||
| Lymphocyte-predominant Hodgkin's lymphoma |
12/13 (92%) | IHC | ||
| Mediastinal large B-cell lymphoma |
9/10 (90%) | IHC |
Bladder cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Invasive urothelial carcinoma |
26/44 (59%) | IHC | 18547613 | |
| Non neoplastic urothelium |
3/69 (4%) | IHC | ||
| Noninvasive high-grade papillary urothelial carcinoma (PUC-H) |
9/17 (53%) | IHC | ||
| Urothelial carcinoma in situ |
14/29 (48%) | IHC | ||
| Urothelial carcinoma |
Metastatic tumor | 26/28 (93%) | IHC | 18347170 |
| Urothelial carcinoma |
Primary tumor | 42/ 214 (20%) | IHC |
Esophageal cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Squamous cell carcinoma |
18/20 (90%) | IHC | 18452554 | |
| Squamous cell carcinoma |
9/10 (90%) | IHC | 19459850 |
Gynecological cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Endometrial carcinosarcoma |
3/5 (60%) | IHC | 18223334 | |
| Endometrial clear cell carcinoma |
9/18 (50%) | IHC | ||
| Endometrial mucinous carcinoma |
0/8 (0%) | IHC | ||
| Endometrial serous carcinoma |
49/51 (94%) | IHC | ||
| Endometrioid carcinoma |
2/70 (3%) | IHC | ||
| Cervical adenocarcinoma in situ |
41/44 (93%) | IHC | 17192788 | |
| Endometrial serous carcinoma |
45/45 (100%) | IHC | 17885673 | |
| Endometrioid carcinoma |
68/122 (56%) | IHC |
Hepatobiliary cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Hepatocellular carcinoma |
255/377 (68%) | IHC | 18802962 |
Kidney cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Chromophobe renal cell carcinoma |
4/26 (15%) | IHC | 16814207 | |
| Clear-cell renal cell carcinoma |
58/252 (23%) | IHC | ||
| Papillary renal cell carcinoma |
7/30 (11%) | IHC | ||
| Unclassified renal cell carcinoma |
2/2 (100%) | IHC | ||
| Clear-cell renal cell carcinoma |
213/716 (30%) | IHC | 18260086 |
Lung cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Adenocarcinoma |
12/14 (86%) | IHC | 12644826 | |
| Squamous cell carcinoma |
11/12 (92%) | IHC | ||
| Atypical carcinoid |
0/21 (0%) | IHC | 17316760 | |
| Large cell neuroendocrine carcinomas (LCNEC) |
9/14 (64%) | IHC | ||
| Small cell lung carcinoma |
10/10 (100%) | IHC |
OTHER CANCER Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Merkel cell carcinoma |
18/20 (90%) | IHC | 18835627 | |
| Mesothelioma |
10/11 (91%) | IHC | 18098206 | |
| Extrapulmonary carcinoid tumor |
0/22 (0%) | IHC | 17521698 | |
| Extrapulmonary small cell carcinoma |
47/53 (89%) | IHC |
Pancreatic cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Ductal carcinoma |
25/26 (96%) | IHC | 15644775 | |
| Invasive mucinous cystadenocarcinoma |
2/2 (100%) | IHC | ||
| Papillary-mucinous carcinoma |
10/10 (100%) | IHC | ||
| Adenocarcinoma |
11/12 (92%) | IHC | 18499984 | |
| Adenocarcinoma |
35/40 (88%) | IHC | 17924416 |
Testicular cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Carcinoma "in situ" |
8/9 (89%) | IHC | 16049158 | |
| Embryonal carcinoma |
7/7(100%) | IHC | ||
| Leydig cell tumor |
1/2 (50%) | IHC | ||
| Seminoma |
3/5 (60%) | IHC | ||
| Spermatocytic seminoma |
1/1 (100%) | IHC | ||
| Teratoma |
8/8 (100%) | IHC |
Available antibodies
anti IMP3 (L523S) monoclonal antibody Corixa Corporation (Seattle, WA)
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