1 |
11/13/2007 |
18000009 |
Testis-expressed protein TSGA10 an auto-antigen in autoimmune polyendocrine syndrome type I. |
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Autoimmune polyendocrine syndrome type 1 (APS1) is a rare monogenic autosomal recessive disorder. Autoimmune gonadal failure is often one of its features. The aim of this study was to identify targets...
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2 |
01/01/2007 |
17920210 |
Expression of two testis-specific genes, TSGA10 and SYCP3, in different cancers regarding to their pathological features. |
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BACKGROUND: Cancer-testis genes are a group of genes expressed in testicular germinal cells and a range of human cancers. Testis-specific gene A10 (TSGA10) is expressed in testis and actively dividing...
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3 |
07/01/2006 |
16406020 |
Expression of the testis-specific gene, TSGA10, in Iranian patients with acute lymphoblastic leukemia (ALL). |
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Testis-specific gene antigen (TSGA10) is expressed in fetus, testis and frequently in human solid cancers and acute leukemias, making it a candidate for immunotherapy and for detection of minimal resi...
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4 |
06/26/2006 |
16777103 |
TSGA10 prevents nuclear localization of the hypoxia-inducible factor (HIF)-1alpha. |
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The hypoxia-inducible factor (HIF)-1 is a transcriptional regulator of genes involved in oxygen homeostasis. We previously described testis-specific isoforms of HIF-1alpha (mHIF-1alphaI.1 and hHIF-1al...
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5 |
06/16/2006 |
16643851 |
Expression of Tsga10 sperm tail protein in embryogenesis and neural development: from cilium to cell division. |
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Tsga10 has been localised in sperm tail as a fibrous sheath protein. In this study, we showed its expression during developmental stages of mouse embryo, in adult mice brain, and in some malignancies....
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6 |
09/01/2005 |
16120156 |
Identification of the testis-specific protein 10 (TSGA10) as serologically defined tumour-associated antigen in primary cutaneous T-cell lymphoma. |
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BACKGROUND: The number of identified tumour-associated antigens for cutaneous lymphoma is still very restricted, which limits the elucidation of the tumour immunology of these malignancies and the dev...
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7 |
03/01/2004 |
14585816 |
Tsga10 encodes a 65-kilodalton protein that is processed to the 27-kilodalton fibrous sheath protein. |
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We had previously reported the isolation of the testis-specific human gene Tsga10, which is not expressed in testes from two infertile patients. To study its role and function, we cloned the mouse hom...
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8 |
01/01/2004 |
15107545 |
Over-expression of the testis-specific gene TSGA10 in cancers and its immunogenicity. |
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The TSGA10 gene was originally isolated in normal testis by differential mRNA display. TSGA10 is located on chromosome 2q11.2 and consists of 19 exons extending over 3 kb. TSGA10 mRNA expression was i...
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9 |
01/10/2001 |
11179690 |
Identification and characterisation of a novel gene, TSGA10, expressed in testis. |
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We describe the isolation of a novel gene, TSGA10, by differential mRNA display which is expressed solely in adult human testis. It seems likely that the gene is expressed during spermatogenesis possi...
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