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List of genes:

Pubmed

Gene: 

NXF2 (official gene symbol)

Other symbol: 

NXF2

CT family: 

CT39 

CT identifier: 

CT39

Aliases from NCBI:

FLJ20416 , TAPL-2

Unified entry for genes NXF2, NXF2B (nearly-identical copies)

11 records found.

ARTICLE DATE PUBMED ID TITLE GENES
1 06/12/2007 17548835 Fragile X mental retardation protein FMRP and the RNA export factor NXF2 associate with and destabilize Nxf1 mRNA in neuronal cells.
  Fragile X syndrome is caused by the inactivation of the X-linked FMR1 gene, leading to the loss of its encoded protein FMRP. Although macroorchidism and defects in neuronal architecture and function h...
2 01/01/2007 17674150 The role of spermatogonially expressed germ cell-specific genes in mammalian meiosis.
  Meiosis, a hallmark of sexual reproduction, reduces the chromatin complement by half to cope with genome doubling at fertilization and permits exchange of genetic material between parental genomes. Re...
3 01/01/2007 17403691 NXF2 is involved in cytoplasmic mRNA dynamics through interactions with motor proteins.
  Tap/NXF1, the founding member of the evolutionarily conserved NXF (Nuclear RNA export Factor) family of proteins, is required for the nuclear export of bulk poly(A)+ RNAs. In mice, three additional NX...
4 08/01/2006 16790844 The fragile X mental retardation protein interacts with a distinct mRNA nuclear export factor NXF2.
  Loss of fragile X mental retardation protein, FMRP, causes the fragile X syndrome. Highly expressed in the brain and testis, FMRP has been implicated in the transport and translation of specific mRNAs...
5 05/01/2005 15820316 Molecular cloning and functional characterization of mouse Nxf family gene products.
  Tap, a member of the evolutionarily conserved nuclear RNA export factor (NXF) family of proteins, has been implicated in the nuclear export of bulk poly(A)+ RNAs. cDNAs encoding the mouse NXF proteins...
6 01/01/2005 16027110 Identification and characterization of the mouse nuclear export factor (Nxf) family members.
  TAP/hNXF1 is a key factor that mediates general cellular mRNA export from the nucleus, and its orthologs are structurally and functionally conserved from yeast to humans. Metazoans encode additional p...
7 06/20/2003 12704671 Five new human cancer-germline genes identified among 12 genes expressed in spermatogonia.
  An important class of tumor-specific antigens is encoded by male germline-specific genes, such as MAGE genes, that are activated in many cancers of various histological types as a result of the demeth...
8 06/15/2003 12784308 Inv(X)(p21.1;q22.1) in a man with mental retardation, short stature, general muscle wasting, and facial dysmorphism: clinical study and mutation analysis of the NXF5 gene.
  We describe a 59-year-old male (patient A059) with moderate to severe mental retardation (MR) and a pericentric inversion of the X-chromosome: inv(X)(p21.1;q22.1). He had short stature, pectus excavat...
9 12/01/2001 11780633 NXF1/p15 heterodimers are essential for mRNA nuclear export in Drosophila.
  The conserved family of NXF proteins has been implicated in the export of messenger RNAs from the nucleus. In metazoans, NXFs heterodimerize with p15. The yeast genome encodes a single NXF protein (Me...
10 09/18/2001 11566096 NXF5, a novel member of the nuclear RNA export factor family, is lost in a male patient with a syndromic form of mental retardation.
  BACKGROUND: Although X-linked mental retardation (XLMR) affects 2%-3% of the human population, little is known about the underlying molecular mechanisms. Recent interest in this topic led to the ident...
11 12/01/2000 11073998 TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture.
  Vertebrate TAP (also called NXF1) and its yeast orthologue, Mex67p, have been implicated in the export of mRNAs from the nucleus. The TAP protein includes a noncanonical RNP-type RNA binding domain, f...