1 |
10/10/2007 |
17928628 |
Alterations in Gene Expression in the Caput Epididymides of Nonobstructive Azoospermic Men. |
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Spermatozoal maturation in the epididymis is dependent on proteins secreted by the epithelium, and those that create the proper ionic composition and pH of the lumen as well as the blood-epididymal ba...
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2 |
09/01/2007 |
17567961 |
Characterization of an eppin protein complex from human semen and spermatozoa. |
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Eppin (SPINLW1; serine peptidase inhibitor-like with Kunitz and WAP domains 1 (eppin); epididymal protease inhibitor) coats the surface of human ejaculate spermatozoa and originates from Sertoli and e...
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3 |
02/15/2007 |
17044815 |
Antimicrobial activity of omwaprin, a new member of the waprin family of snake venom proteins. |
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We have isolated and characterized omwaprin, a 50-amino-acid cationic protein from the venom of inland taipan (Oxyuranus microlepidotus). It is a new member of the waprin family of snake venom protein...
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4 |
02/01/2007 |
17345778 |
[Advances in the studies of epididymal protease inhibitor--Eppin] |
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The epididymal protease inhibitor (Eppin) abounds in human semen and on the surface of human spermatozoa, specifically produced by the testis and epididymis. Recombinant Eppin has effected infertility...
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5 |
01/01/2007 |
17644992 |
Eppin: a molecular strategy for male contraception. |
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New male contraceptives, both hormonal and non-hormonal, have many obstacles to overcome before they reach the market as a product. For hormonal contraceptives the long-term efficacy of oligospermia i...
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6 |
01/01/2007 |
17566290 |
Eppin: an epididymal protease inhibitor and a target for male contraception. |
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Eppin (epididymal protease inhibitor) is one of several serine protease (or serine protease-like) inhibitors that are encoded by genes on human chromosome 20 and on mouse chromosome 2. Here we review ...
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7 |
05/16/2006 |
16423450 |
Eppin: an effective target for male contraception. |
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Eppin (epididymal protease inhibitor) is a member of the whey acidic protein (WAP)-type four-disulfide core (WFDC) gene family. This study provides updated information on Eppin and the Eppin-like gene...
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8 |
05/01/2006 |
16755874 |
[Correlation of epididymal protease inhibitor Eppin and Semenogelin on human ejaculated spermatozoa] |
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OBJECTIVE: To evaluate the correlation of epididymal protease inhibitor(Eppin) and Semenogelin(Sg) on human ejaculated spermatozoa. METHODS: The experimental approaches include: (1) Immunoprecipitatio...
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9 |
11/01/2005 |
16333968 |
[Advances in the study of epididymal protease inhibitor] |
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The epididymal protease inhibitor (Eppin) has recently been cloned in human and mice, which is specifically expressed in the epididymis and testis. Eppin is a cystine-rich secretory protein which cont...
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10 |
11/01/2005 |
16230226 |
Reversible, non-barrier male contraception: status and prospects. |
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OBJECTIVE: Male, non-barrier, contraceptive options are limited to vasectomy and inadequate methods such as withdrawal and periodic abstinence. Herein we give an overview of current research on male c...
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11 |
05/01/2005 |
15590901 |
Association of eppin with semenogelin on human spermatozoa. |
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Eppin (SPINLW1; GeneID, 57119) is a single-copy gene encoding a cysteine-rich protein found only in the testis and epididymis, which contains both Kunitz-type and WAP-type four disulfide core protease...
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12 |
12/01/2004 |
15625390 |
Eppin: a candidate male contraceptive vaccine? |
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13 |
11/12/2004 |
15539605 |
Reversible immunocontraception in male monkeys immunized with eppin. |
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Various forms of birth control have been developed for women; however, there are currently few options for men. The development of male contraceptives that are effective, safe, and reversible is desir...
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14 |
11/01/2004 |
15229136 |
Antimicrobial activity of human EPPIN, an androgen-regulated, sperm-bound protein with a whey acidic protein motif. |
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The role of epididymal sperm-binding proteins in reproductive tract immunity is now well recognized in addition to their role in sperm maturation. Spermatozoa acquire forward motility and fertilizing ...
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15 |
07/17/2003 |
12909348 |
Characterization of mouse Eppin and a gene cluster of similar protease inhibitors on mouse chromosome 2. |
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We have recently described a novel gene on human chromosome 20q 12-13.2 called Eppin (Epididymal protease inhibitor) that expresses three mRNAs encoding two isoforms of a cysteine-rich protein contain...
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16 |
02/15/2003 |
12574366 |
Mouse SWAM1 and SWAM2 are antibacterial proteins composed of a single whey acidic protein motif. |
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Antibacterial proteins are important participants in the innate immunity system. Elafin and SLPI are the whey acidic protein (WAP) motif proteins with both antibacterial activity and antiprotease acti...
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17 |
11/15/2002 |
12206714 |
A locus on human chromosome 20 contains several genes expressing protease inhibitor domains with homology to whey acidic protein. |
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A locus containing 14 genes, encoding protein domains that have homology with whey acidic protein (WAP), has been identified in a region of 678 kb on human chromosome 20q12-13.1. Among them are genes ...
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18 |
05/30/2001 |
11404006 |
Cloning and sequencing of human Eppin: a novel family of protease inhibitors expressed in the epididymis and testis. |
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In this report we describe the discovery of Eppin (Epididymal protease inhibitor), a gene on human chromosome 20 expressing three mRNAs encoding two isoforms of a cystine-rich protein containing both ...
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