CTDatabase

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List of genes:

B
- BAGEAlias:BAGE1
- BAGE2
- BAGE3
- BAGE4
- BAGE5
- BRDTAlias:BRD6

E
- EDAG, NDR
- ELOVL4

I
- IGSF11
- IL13RA2
- IMP-3

J
- JARID1BAlias:FLJ10538, FLJ12459, FLJ12491, FLJ16281, FLJ23670, KDM5B, PLU-1, PUT1, RBBP2H1A

K
- KIAA0100

V
- VENTXP1Alias:NA88A, VENTX2P1

Z
- ZNF165Alias:LD65, ZSCAN7
- ZNF645

Protein

Gene:

HEMGN (official gene symbol)

Other symbol:

EDAG, NDR

CT family:

HEMGN

CT identifier:

CT155

RefSeq :

Cellular localization

Subcellular Localization	Cell type	Methodology	PMID
nucleus	HEK293 cell line	IF and confocal microscopy	11404085

Protein function and interaction

HEMGN plays an important role in hematopoietic development (Yang et al., 2001 PMID:11404085). HEMG functions as a positive regulator of erythroid/megakaryocytic differentiation in myeloid cells associated with the induction of GATA-1 and its target genes (Ding et al., 2010 PMID:20564185). HEMGN binds to and enhances the protein stability of NPM1 (nucleophosmin ⁄B23) which plays a critical role in the anti-apoptosis of leukaemia cells (Zhang et al., 2012 PMID:22712502).