Protein expression
Gene:
CTAG1B (official gene symbol)Other symbol:
CTAG1BCT family:
CT6CT identifier:
CT6.1Aliases from NCBI:
CTAG , CTAG1 , ESO1 , LAGE-2 , LAGE2B , NY-ESO-1Unified entry for genes CTAG1B, CTAG1A (nearly-identical copies)
Published data of protein expression in normal tissues
Show| Tissue | Methodology | PMID |
|---|---|---|
| Testis | IHC mAb D8-38 | 12065688 |
| Fetal testis | IHC mAb D8-38 | 12065688 |
| Testis | IHC mAB E978 ( Zymed Laboratories Inc.) | 17208940 |
| Fetal testis | IHC mAB E978 ( Zymed Laboratories Inc.) | 17208940 |
| Fetal ovary | IHC mAB E978 ( Zymed Laboratories Inc.) | 17208940 |
| Fetal ovary | IHC mAB ES121 | 17217256 |
| Testis | IHC mAB ES121 | 11351307 |
| Fetal ovary | IHC | 17274819 |
| Placenta | IHC mAB E978 | 17715884 |
| Mesenchymal stem cells | Immunofluorescence | 15781633 |
| Fetal testis | IHC | 22016418 |
| Fetal ovary | IHC | 22016418 |
| Testis (pre-meiotic germ cells) | IHC | 22016418 |
Published data of protein expression in neoplasias
Hematologic malignacies Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Myeloma |
47/55 (85%) | IHC mAb B9.8 | 15671442 | |
| Plasma cell myeloma |
17/203 (8%) | IHC | 18307538 | |
| Non-Hodgkin�s lymphoma |
4/106 (5 %) | Tissue microarray (IHC) | 22638551 | |
| Diffuse large B-cell testicular lymphoma |
9/24 (37%) | IHC | 23680437 |
Brain cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Astrocytoma |
14/14 (100%) | IHC | 18396787 | |
| Medulloblastomas/ Primitive neuroectodermal tumors |
6 ⁄6 (100%) | IHC | ||
| Medulloblastomas |
0/25 (0%) | IHC mAB E978 | 18426187 |
Breast cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Breast carcinoma |
Metastatic tumor | 6/53 (11%) | IHC | 19651608 |
| Breast carcinoma |
Primary tumor | 13/201 (6%) | IHC | |
| Invasive breast carcinoma (IBC) |
ER-positive tumors | 2/50 (4%) | IHC | 20610479 |
| Invasive breast carcinoma (IBC) |
ER/PR/HER2 triple-negative tumors | 9/50 (18%) | IHC | |
| Invasive ductal carcinoma |
ER-negative tumors | 47/265 (18%) | IHC | 21437249 |
| Invasive ductal carcinoma |
ER-positive tumors | 4/189 (2%) | IHC | |
| Invasive ductal carcinoma |
ER/PR/HER2 triple-negative tumors | 43/225 (19%) | IHC | |
| Breast carcinoma |
BRCA-associated tumors | 10/26 (38%) | IHC | 21465317 |
| Medullary breast cancer |
11/49 (22%) | IHC | 21495200 | |
| Breast carcinoma |
14/164 (8%) | IHC | 22116775 | |
| Breast carcinoma |
Primary invasive | 21/140 (15%) | Tissue microarray (IHC) | 23731661 |
Gastric cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Gastrointestinal stromal tumor (GIST) |
10/86 (12%) | IHC | 21140451 |
Gynecological cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Vulvar squamous cell carcinoma |
1/76 (1.3%) | IHC | 21323970 |
Head & Neck cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Pharyngeal squamous cell carcinoma |
30/90 (33%) | IHC | 20029985 | |
| Squamous cell carcinoma of the larynx |
6/63 (9%) | IHC | 20886663 |
Hepatobiliary cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Hepatocellular carcinoma |
3/18 (17%) | IHC mAB ES121 | 16872310 | |
| Hepatocellular carcinoma |
25/132 (19%) | IHC | 15890110 | |
| Cholangiocarcinoma |
0/50 (0%) | IHC | 18942708 | |
| Gallbladder carcinoma |
1/32 (3%) | IHC | ||
| Hepatocellular carcinoma |
3/146 (2%) | IHC | ||
| Intrahepatic cholagiocarcinoma |
20/89 (22%) | IHC | 21211023 | |
| Hepatocellular carcinoma |
28/120 (23%) | IHC | 22740853 |
Kidney cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Chromophobe renal cell carcinoma (ChRCC) |
6/18 (33%) | IHC | 20591578 | |
| Renal oncocytoma (RO) |
15/17 (88%) | IHC |
Lung cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Lung carcinoma |
2/16 (12.5%) | IHC mAB E978 | 16596224 | |
| Non small cell lung carcinoma |
15/130 (12%) | IHC mAb D8-38 | 15751033 | |
| Adenocarcinoma |
11% | IHC | 18982744 | |
| Squamous cell carcinoma |
23% | IHC | ||
| Adenocarcinoma |
9/57 (16%) | IHC | 19795170 | |
| Squamous cell carcinoma |
15/75 (20%) | IHC | ||
| Adenocarcinoma |
7/90 (8%) | Microarray | 22922091 | |
| Squamous cell carcinoma |
20/89 (22%) | Microarray |
Melanocytic lesion Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Head and neck melanoma |
17/70 (24%) | IHC mAB ES121 | 15515159 | |
| Melanoma |
6/6 (100%) | IHC mAB ES121 | 14646623 | |
| Melanoma |
Metastatic tumor | 18/56 (32%) | IHC mAB E978 | 17625806 |
| Melanoma |
Primary tumor | 8/61 (13%) | IHC mAB E978 | |
| Desmoplastic melanoma |
3/32 (9%) | IHC mAB E978 | 16845331 | |
| Melanoma |
Metastatic tumor | 45% | IHC mAB E978 | 16467087 |
| Melanoma |
Primary tumor | 45% | IHC mAB E978 | |
| Melanoma |
12/38 (38%) | IHC mAb D8-38 | 15751033 | |
| Melanoma |
43/54 (80%) | IHC mAB E978 | 15623618 | |
| Melanoma |
120/321 (37%) | IHC | 21115342 | |
| Conjunctival melanoma |
0/15 (0%) | RT-PCR | 22190731 | |
| Uveal melanoma |
0/32 (0%) | RT-PCR |
OTHER CANCER Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Gastrointestinal stromal tumor (GIST) |
7/35 (20%) | IHC | 18646188 | |
| Gastrointestinal stromal tumor (GIST) |
7/35 (20%) | IHC | 19190130 |
Ovarian cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Ovarian germ cell tumor |
0/60 (0%) | IHC mAb ES 121 | 17274819 | |
| Ovarian carcinoma |
50/117 (43%) | IHC mAB ES121 | 16344461 | |
| Serous carcinoma |
10/53 (19%) | IHC mAb D8-38 | 14695148 | |
| Ovarian carcinoma |
62/143 (43%) | IHC mAB ES121 | 14522938 | |
| Epithelial ovarian cancer |
5/34 (15%) | IHC | 18923710 | |
| Ovarian carcinoma |
Recurrent tumor | 7/80 (9 %) | IHC | 23529156 |
| Ovarian carcinoma |
Primary tumor | 16/230 (7 %) | IHC |
Sarcoma Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Myxoid/round cell liposarcoma |
25/25 (100%) | IHC | 22359263 | |
| Myxoid/round cell liposarcoma |
16/18 (89%) | IHC | 22936067 | |
| Extra-cardiac soft tissue myxoma |
0/39 (0%) | IHC | 23599152 | |
| Extraskeletal myxoid chondrosarcoma |
0/12 (0%) | IHC | ||
| Lipoma |
0/20 (0%) | IHC | ||
| Low-grade fibromyxoid sarcoma |
0/7 (0%) | IHC | ||
| Myxofibrosarcoma |
0/10 (0%) | IHC | ||
| Myxoid/round cell liposarcoma |
36/38 (95%) | IHC |
Testicular cancer Show
Published data of protein expression in Cell Lines
Show| Origin tissue | Cell Line ID | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Melanoma | Tu379 BL-Mel |
2/2 (100%) | Immunofluorescence | 15781633 |
Available antibodies
mAB E978 monoclonal antibody (Stockert et al, 1998 PMID: 9547346)
mAb D8-38 monoclonal antibody (Jungbluth et al, 2001 PMID: 11351307)
mAB ES121 monoclonal antibody (Jungbluth et al, 2001 PMID: 11351307)
2005-2009© CT Antigens Database