| 1 |
09/01/2007 |
17509725 |
Immunization of NSCLC patients with antigen-pulsed immature autologous dendritic cells. |
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Only a handful of NSCLC patients have been included in dendritic cell (DC) vaccine clinical trials. We had previously reported a series of 16 individuals with stages IA-IIIB NSCLC who received autolog...
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| 2 |
07/25/2006 |
16847267 |
MAGE-A tumor antigens target p53 transactivation function through histone deacetylase recruitment and confer resistance to chemotherapeutic agents. |
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The MAGE gene family is characterized by a conserved domain (MAGE Homology Domain). A subset of highly homologous MAGE genes (group A; MAGE-A) belong to the chromosome X-clustered cancer/testis antige...
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| 3 |
07/15/2004 |
15254048 |
Autologous dendritic cell vaccines for non-small-cell lung cancer. |
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PURPOSE: Therapeutic outcomes of definitively treated non-small-cell lung cancer (NSCLC) are unacceptably poor. A wealth of preclinical information, and a modest amount of clinical information indicat...
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| 4 |
03/01/2004 |
15160996 |
Cytotoxic T cell induction against human malignant melanoma cells using HLA-A24-restricted melanoma peptide cocktail. |
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Many human leukocyte antigen (HLA)-class I (mainly A*0201)-restricted peptide-specific cytotoxic T cells (CTLs) have been derived from peripheral blood lymphocytes (PBLs) of melanoma patients. However...
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| 5 |
07/01/2003 |
12855658 |
Overexpression of MAGE/GAGE genes in paclitaxel/doxorubicin-resistant human cancer cell lines. |
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Previous studies directed at identifying paclitaxel resistance genes in a paclitaxel-resistant subclone of the human ovarian cancer cell line SKOV-3 identified a novel cancer testis antigen, Taxol res...
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| 6 |
01/01/2002 |
11924907 |
Promoter methylation controls the expression of MAGE2, 3 and 4 genes in human cutaneous melanoma. |
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Cancer-testis antigens expressed by different-histotype transformed cells are suitable targets for tumor immunotherapy. However, their heterogeneous expression in neoplastic lesions limits the eligibi...
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| 7 |
07/15/2001 |
11441084 |
Identification of new epitopes from four different tumor-associated antigens: recognition of naturally processed epitopes correlates with HLA-A*0201-binding affinity. |
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Forty-two wild-type and analogue peptides derived from p53, carcinoembryonic Ag, Her2/neu, and MAGE2/3 were screened for their capacity to induce CTLs, in vitro, capable of recognizing tumor target li...
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| 8 |
08/01/1999 |
10500969 |
[Molecular staging of testicular cancer using polymerase chain reaction of the testicular cancer-specific genes] |
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Most testicular germ cell tumors have serological tumor markers such as alpha-fetoprotein (AFP) and human chorionic gonadotropin beta-subunit (beta-HCG). On the other hand, molecular staging of these ...
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| 9 |
01/01/1998 |
9544234 |
The multi-epitope approach for immunotherapy for cancer: identification of several CTL epitopes from various tumor-associated antigens expressed on solid epithelial tumors. |
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One approach to development of specific cancer immunotherapy relies on the induction of cytotoxic T lymphocytes (CTL) specific for tumor-associated antigens (TAA). Induction of TAA-specific CTL could ...
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| 10 |
01/01/1994 |
8276455 |
Sequence and expression pattern of the human MAGE2 gene. |
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We reported previously identification of the human MAGE1 gene, which encodes an antigen recognized on human melanoma MZ2-MEL by autologous cytolytic T lymphocytes. In addition to MAGE1, melanoma MZ2-M...
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