1 |
08/01/2007 |
17397028 |
Identification of cytotoxic T-lymphocyte epitope(s) and its agonist epitope(s) of a novel target for vaccine therapy (PAGE4). |
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PAGE4 is an X chromosome-linked cancer testis antigen and is a potential new tumor-associated antigen that is overexpressed in prostate and uterine cancers. The purpose of this study was to identify a...
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2 |
01/01/2007 |
17113629 |
GAGEC1, a cancer/testis associated antigen family member, is a target of TGF-beta1 in age-related prostatic disease. |
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Transforming growth factor beta (TGF-beta) is a multi-functional cytokine that plays a fundamental role during embryonic development and tissue homeostasis in metazoans. Changes in TGF-beta signalling...
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3 |
04/01/2005 |
15705628 |
Gene expression studies provide clues to the pathogenesis of uterine leiomyoma: new evidence and a systematic review. |
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BACKGROUND: Uterine leiomyomas are extremely common and a major cause of pelvic pain, bleeding, infertility, and the leading indication for hysterectomy. Familial and epidemiological studies provide c...
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4 |
01/01/2005 |
15610763 |
Profiling molecular targets of TGF-beta1 in prostate fibroblast-to-myofibroblast transdifferentiation. |
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The development of age-related proliferative disorders of the prostate gland is supported by transdifferentiation and cellular senescence processes in the stroma. Both processes are involved in remode...
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5 |
01/01/2005 |
15557110 |
Tales from the crypt: beta-catenin in the development of juvenile polyps: commentary on the article by Iwamoto et al. on page 4. |
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6 |
08/01/2004 |
15459874 |
[Adaptive immunotherapy of the advanced prostate cancer - cancer testis antigen (CTA) as possible target antigens] |
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Prostate cancer (PCa) like other tumors expresses antigens that may serve as target for specific immunotherapy. Special antigen-presenting cells (e. g., dendritic cells) are capable of generating tumo...
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7 |
07/01/2002 |
12095500 |
Insights from gene arrays on the development and growth regulation of uterine leiomyomata. |
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OBJECTIVE: To use microarray analysis as an unbiased approach to identify genes involved in the induction and growth of uterine leiomyomata. DESIGN: Screen by arrays for up to 12,000 genes in leiomyom...
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8 |
03/01/2002 |
12489849 |
PAGE4 is a cytoplasmic protein that is expressed in normal prostate and in prostate cancers. |
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PAGE4 is an X chromosome-linked cancer-testis antigen that was identified by expressed sequence tags database mining and a functional genomic approach. PAGE4 is preferentially expressed in normal male...
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9 |
10/01/2001 |
11746119 |
Novel feto-specific mRNA species suitable for identification of fetal cells from the maternal circulation. |
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Feto-specific markers are necessary for genetic diagnostics on fetal cells isolated from maternal blood. Differential display reverse transcription-polymerase chain reaction (DDRT-PCR) was used to ide...
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10 |
06/01/2001 |
11384102 |
Identification of potential diagnostic markers of prostate cancer and prostatic intraepithelial neoplasia using cDNA microarray. |
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The identification of novel genes or groups of genes expressed in prostate cancer may allow earlier diagnosis or more accurate staging of the disease. We describe the assembly and use of a 1877-member...
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11 |
10/01/1992 |
1397482 |
Purification of lysosomal arylsulfatase B from rat liver and its reactivity with lectins in affinity immunoelectrophoresis. |
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1. Arylsulfatase B (ASB) from lysosomal fraction of rat liver were isolated and purified 260-fold with a recovery of about 5%. 2. The enzyme in gradient PAGE 4-30% followed by immunoelectrophoresis mi...
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12 |
05/01/1991 |
1821698 |
Psychotropic effects of ritanserin, a selective S2 antagonist: an open study. |
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The efficacy of the S2-antagonist ritanserin has not yet been clarified satisfactorily. In an open indication finding study to generate new hypotheses concerning its possible therapeutic application c...
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13 |
07/01/1989 |
12695784 |
Toxicology and Carcinogenesis Studies of Hydrochlorothiazide (CAS No. 58-93-5) in F344/N Rats and B6C3F1 Mice (Feed Studies). |
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Hydrochlorothiazide is a diuretic active at the distal convoluted tubule and collecting duct. Toxicology and carcinogenesis studies were conducted by feeding diets containing hydrochlorothiazide (USP ...
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14 |
05/01/1989 |
12695783 |
Toxicology and Carcinogenesis Studies of Ochratoxin A (CAS No. 303-47-9) in F344/N Rats (Gavage Studies). |
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Ochratoxin A is a naturally occurring fungal toxin that is a contaminant in corn, peanuts, storage grains, cottonseed, meats, dried fish, and nuts. Toxicology and carcinogenesis studies were conducted...
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15 |
07/01/1986 |
10278522 |
The competitive health care marketplace: bringing new challenges to a changing field. |
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This article, in response to Dr. Weil's article (beginning on page 4), explores the changing health care industry from a different perspective. Stressed here is the need fro hospitals to join an integ...
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16 |
07/01/1974 |
4846473 |
[Continuity of bed and ambulatory part of the care of patients with blood circulatory diseases in old age (on the article of Prof. Vl. Pacovsky: "Concept of hospital care in internal medicine", Vnitrní Lék., 19, 1973, 1, page 4-7)] |
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