1 |
12/01/2007 |
17487488 |
HAGE, a cancer/testis antigen with potential for melanoma immunotherapy: identification of several MHC class I/II HAGE-derived immunogenic peptides. |
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There remains a need to identify novel epitopes of potential tumour target antigens for use in immunotherapy of cancer. Here, several melanoma tissues and cell lines but not normal tissues were found ...
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2 |
03/01/2007 |
17312182 |
Cancer/testis genes in multiple myeloma: expression patterns and prognosis value determined by microarray analysis. |
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Cancer-testis (CT) Ags are expressed in testis and malignant tumors but rarely in nongametogenic tissues. Due to this pattern, they represent attractive targets for cancer vaccination approaches. The ...
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3 |
02/01/2007 |
17296563 |
Epigenetic regulation of human cancer/testis antigen gene, HAGE, in chronic myeloid leukemia. |
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BACKGROUND AND OBJECTIVES: Cancer testis antigens (CTA) provide attractive targets for cancer-specific immunotherapy. Although CTA genes are expressed in some normal tissues, such as the testis, this ...
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4 |
12/01/2003 |
14624785 |
SAGE mRNA expression in advanced-stage lung cancers. |
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AIMS: SAGE and HAGE are recently isolated genes, which were thought to be expressed tumour-specifically, and are potentially coding for tumour-specific antigens recognized by T lymphocytes. The expres...
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5 |
08/01/2003 |
12890744 |
Analysis of the tumour suppressor genes, FHIT and WT-1, and the tumour rejection genes, BAGE, GAGE-1/2, HAGE, MAGE-1, and MAGE-3, in benign and malignant neoplasms of the salivary glands. |
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AIMS: Molecular genetic changes involved in tumorigenesis and malignant transformation of human tumours are novel targets of cancer diagnosis and treatment. This study aimed to analyse the expression ...
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6 |
11/01/2002 |
12399967 |
Frequent expression of HAGE in presentation chronic myeloid leukaemias. |
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Cancer testis (CT) antigens provide attractive targets for cancer-specific immunotherapy. Although CT genes are expressed in some normal tissues, such as the testis and in some cases placenta, these i...
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7 |
07/15/2000 |
10919659 |
Identification on a human sarcoma of two new genes with tumor-specific expression. |
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Genes MAGE, BAGE, GAGE, and LAGE-1/NY-ESO-1 code for antigens that are recognized on melanoma cells by autologous CTLs. Because the pattern of expression of these genes results in the presence of anti...
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