| 1 | 11/01/2007 | 17981135 | Human Blinkin/AF15q14 is required for chromosome alignment and the mitotic checkpoint through direct interaction with Bub1 and BubR1. |  | 
 
                  |  | The spindle checkpoint controls mitotic progression. Checkpoint proteins are temporally recruited to kinetochores, but their docking site is unknown. We show that a human kinetochore oncoprotein, AF15... 
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                  | 2 | 12/01/2004 | 15579588 | The protein encoded by cancer/testis gene D40/AF15q14 is localized in spermatocytes, acrosomes of spermatids and ejaculated spermatozoa. |  | 
 
                  |  | We have previously identified and cloned a human gene, D40, that is preferentially expressed in testis among normal organs, while it is widely expressed in various human tumor cell lines and primary t... 
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                  | 3 | 11/01/2004 | 15502821 | A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1. |  | 
 
                  |  | Defects in kinetochore proteins often lead to aneuploidy and cancer. Mis12-Mtw1 is a conserved, essential kinetochore protein family. Here, we show that a Mis12 core complex exists in Schizosaccharomy... 
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                  | 4 | 03/06/2003 | 12618766 | A t(11;15) fuses MLL to two different genes, AF15q14 and a novel gene MPFYVE on chromosome 15. |  | 
 
                  |  | The mixed lineage leukemia gene (MLL, also known as HRX, ALL-1 and Htrx) located at 11q23 is involved in translocations with over 40 different chromosomal bands in a variety of leukemia subtypes. Here... 
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                  | 5 | 06/05/2002 | 12087463 | Frequent expression of new cancer/testis gene D40/AF15q14 in lung cancers of smokers. |  | 
 
                  |  | We found a significant correlation between lung cancer in smokers and the expression of a human gene, D40, predominantly expressed in testis and cancers. In an attempt to clone a novel human gene, we ... 
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                  | 6 | 03/01/2002 | 11857474 | Isolation of the peri-acrosomal plasma membrane protein D40 enriched fraction from guinea pig spermatozoa using a monoclonal antibody. |  | 
 
                  |  | Membrane fragments were obtained from guinea pig spermatozoa by mechanical shearing. A membrane-enriched fraction was separated from other cellular debris, mainly sperm nuclei and tails, by centrifuga... 
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                  | 7 | 09/07/2000 | 10980622 | AF15q14, a novel partner gene fused to the MLL gene in an acute myeloid leukaemia with a t(11;15)(q23;q14). |  | 
 
                  |  | In haematopoietic malignancies the MLL gene, located on chromosome 11q23, is frequently disrupted by chromosome rearrangement, generally resulting in fusion to various partner genes. We have previousl... 
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                  | 8 | 01/01/1999 | 10780384 | Chromosomal assignment of a novel human gene D40. |  | 
 
                  |  | We have previously reported an identification of a novel human cellular factor, D40. Here, we report the chromosomal localization of the gene that encodes D40. Fluorescent in situ hybridization (FISH)... 
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                  | 9 | 01/01/1999 | 10780383 | Isolation of cDNAs that cover the entire coding region of a novel human protein D40. |  | 
 
                  |  | Previously, we have reported a novel protein, D40, that specifically binds to a nuclear factor GCF by two-hybrid system. Northern analysis on tumor cell lines revealed that mRNA of D40 is about 5 kb. ... 
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