Protein expression
Gene:
MAGEA3 (official gene symbol)Other symbol:
MAGEA3CT family:
CT1CT identifier:
CT1.3Aliases from NCBI:
HIP8 , HYPD , MAGE3 , MGC14613Published data of protein expression in normal tissues
ShowPublished data of protein expression in neoplasias
Hematologic malignacies Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Myeloma |
6/10 (60%) | Western blot | 19190130 |
Bladder cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Transitional cell carcinoma |
54/102 (53%) | Western blot | 21396841 |
Brain cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Medulloblastomas |
1/25 (4%) | IHC mAB M3H67 | 18426187 |
Colon & Rectum cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Adenocarcinoma of the large intestine |
1/27 (4%) | IHC | 23390371 |
Gastric cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Gastrointestinal stromal tumor (GIST) |
7/86 (8%) | IHC | 21140451 |
Head & Neck cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Squamous cell carcinoma of the larynx |
23/63 (36%) | IHC | 20886663 |
Hepatobiliary cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Hepatocellular carcinoma |
9/15 (60%) | Western blot | 10576668 | |
| Intrahepatic cholagiocarcinoma |
24/89 (27%) | IHC | 21211023 |
Lung cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Adenocarcinoma |
19% | IHC | 18982744 | |
| Squamous cell carcinoma |
65% | IHC | ||
| Adenocarcinoma |
18/57 (32%) | IHC | 19795170 | |
| Squamous cell carcinoma |
48/75 (64%) | IHC |
Melanocytic lesion Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Melanoma |
Primary tumor | 4/26(15%) | IHC mAB M3H67 | 15606517 |
| Nevus |
0 /19 (0%) | IHC mAB M3H67 | ||
| Melanoma |
Oesophageal mucosa | 6/6 (100%) | IHC mAB M3H67 | 14646623 |
| Melanoma |
Metastatic tumor | 116/191 (60.7%) | IHC mAB 57B | 16567969 |
| Melanoma |
14/31 (45%) | FACS | 15305155 | |
| Melanoma |
Skin metastasis | 47/52 (90%) | IHC mAB 57B | 15570431 |
| Conjunctival melanoma |
5/15 (33%) | RT-PCR | 22190731 | |
| Uveal melanoma |
0/32 (0%) | RT-PCR |
OTHER CANCER Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Gastrointestinal stromal tumor (GIST) |
5/35 (14%) | IHC | 19190130 |
Sarcoma Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Gastrointestinal stromal tumor (GIST) |
5/35 (14%) | IHC | 18646188 |
Published data of protein expression in Cell Lines
Show| Origin tissue | Cell Line ID | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Head and neck squamous cell carcinoma | PCI-30 PCI-13 |
Western blot | 19610063 | |
| mouse melanoma | B16-HLA-MAGE-3 | Western blot | 18616910 | |
| Myeloma | U266 | Western blot | 19190130 |
Available antibodies
57B monoclonal antibody Kocher et al, 1995 PMID: 7757970 (detects several MAGE-A antigens)
M3H67 monoclonal antibody Chitale et al, 2005 PMID: 15272278
2005-2009© CT Antigens Database