Protein expression
Gene:
MAGEC1 (official gene symbol)Other symbol:
MAGEC1CT family:
CT7CT identifier:
CT7.1Aliases from NCBI:
CT7 , MAGE-C1 , MGC39366Published data of protein expression in normal tissues
Show| Tissue | Methodology | PMID |
|---|---|---|
| Placenta | IHC mAb CT7-33 | 17715884 |
| Testis | IHC mAb CT7-33 | 12115486 |
| Testis (pre-meiotic germ cells) | IHC | 22016418 |
| Fetal testis | IHC | 22016418 |
| Fetal ovary (oogonia and pre-granulosa cells) | IHC | 22016418 |
Published data of protein expression in neoplasias
Hematologic malignacies Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Monoclonal gammopathy of undetermined significance (MGUS) |
2/15 (13%) | IHC mAb CT7-33 | 15761016 | |
| Myeloma |
27/33 (82%) | IHC mAb CT7-33 | ||
| Extramedullary plasmacytoma |
3/4 (75%) | IHC mAb CT7-33 | 12875607 | |
| Myeloma |
9/13 (69%) | IHC mAb CT7-33 | ||
| Plasmacytoma |
11/12 (92%) | IHC mAb CT7-33 | ||
| Plasma cell myeloma |
97/169 (57%) | IHC | 18307538 | |
| Myeloma |
14/24 (58%) | IHC | 18323799 | |
| Myeloma |
10/10 (100%) | Western blot | 19190130 | |
| Myeloma |
Bone marrow | 18/24 (75%) | IHC | 20621094 |
| Myeloma |
Osteolytic lesions | 48 /105 (46%) | IHC | |
| Hodgkin's lymphoma |
5/38 (13%) | Tissue microarray (IHC) | 21951388 | |
| Classical Hodgkin’s lymphoma |
5/38 (13%) | Tissue microarray (IHC) | 21898529 | |
| Non-Hodgkin�s lymphoma |
3/106 (4%) | Tissue microarray (IHC) | 22638551 | |
| Light-chain amyloidosis (AL amyloidosis) |
25/38 (66%) | IHC | 22983433 |
Brain cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Medulloblastomas |
1/25 (4%) | IHC mAb CT7-33 | 18426187 |
Breast cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Invasive ductal carcinoma |
ER-negative tumors | 50/265 (19%) | IHC | 21437249 |
| Invasive ductal carcinoma |
ER-positive tumors | 12/189 (6%) | IHC | |
| Invasive ductal carcinoma |
ER/PR/HER2 triple-negative tumors | 32/225 (14%) | IHC |
Gastric cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Gastrointestinal stromal tumor (GIST) |
13/86 (15%) | IHC | 21140451 |
Head & Neck cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Squamous cell carcinoma of the larynx |
5/63 (8%) | IHC | 20886663 | |
| Squamous cell carcinoma of the larynx |
14/63 (22%) | IHC | ||
| Oral squamous cell carcinoma |
11/23 (48%) | IHC | 22083937 |
Hepatobiliary cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Cholangiocarcinoma |
0/50 (0%) | IHC | 18942708 | |
| Hepatocellular carcinoma |
17/146 (12%) | IHC |
Lung cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Adenocarcinoma |
6/90 (7%) | Microarray | 22922091 | |
| Squamous cell carcinoma |
10/89 (11%) | Microarray |
Melanocytic lesion Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Melanoma |
Primary tumor | 10/26(38%) | IHC mAb CT7-33 | 15606517 |
| Nevus |
0 /19 (0%) | IHC mAb CT7-33 | ||
| Melanoma |
Oesophageal mucosa | 6/6 (100%) | IHC mAb CT7-33 | 14646623 |
| Melanoma |
Metastatic tumor | 65/163 (40%) | Tissue microarray (IHC) | 21738656 |
| Melanoma |
Primary tumor | 15/50 (24%) | Tissue microarray (IHC) | |
| Conjunctival melanoma |
3/15 (20%) | IHC | 22190731 | |
| Uveal melanoma |
0/32 (0%) | IHC |
OTHER CANCER Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Gastrointestinal stromal tumor (GIST) |
9/35 (26%) | IHC | 19190130 |
Ovarian cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Ovarian carcinoma |
Recurrent tumor | 28/80 (35 %) | IHC | 23529156 |
| Ovarian carcinoma |
Primary tumor | 56/230 (24%) | IHC |
Sarcoma Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Gastrointestinal stromal tumor (GIST) |
9/35 (26%) | IHC | 18646188 |
Testicular cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Seminona (classical) |
67/73 (92%) | IHC | 22016418 |
Published data of protein expression in Cell Lines
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