| 1 |
03/01/2007 |
17312182 |
Cancer/testis genes in multiple myeloma: expression patterns and prognosis value determined by microarray analysis. |
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Cancer-testis (CT) Ags are expressed in testis and malignant tumors but rarely in nongametogenic tissues. Due to this pattern, they represent attractive targets for cancer vaccination approaches. The ...
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| 2 |
01/01/2007 |
17607369 |
Expression of cancer-testis antigen CT7 (MAGE-C1) in breast cancer: an immunohistochemical study with emphasis on prognostic utility. |
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High expression of the cancer-testis antigen CT7, also referred to as MAGE-C1, has been recently described in a variety of malignant tumors, including breast carcinoma. To our knowledge, no data conce...
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| 3 |
01/01/2007 |
17217256 |
Cancer/testis (CT) antigens are expressed in fetal ovary. |
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Cancer/testis (CT) antigens are named after their expression pattern as they are typically present in various types of tumors and in the germ cells of normal adult testis. Adult ovarian tissue is usua...
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| 4 |
09/15/2006 |
17000678 |
Cancer-testis antigens: expression and correlation with survival in human urothelial carcinoma. |
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PURPOSE: Vaccination against human cancer is a promising therapeutic approach but the optimal antigen or antigens remain undefined. Cancer-testis antigens (CTA), a family of tumor-associated antigens,...
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| 5 |
09/01/2006 |
16929165 |
Expression of cancer-testis antigens as possible targets for antigen-specific immunotherapy in head and neck squamous cell carcinoma. |
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Cancer-Testis (CT) antigens are by definition expressed in tumor but not in healthy tissue except testis and might represent ideal targets for antigen-specific immunotherapy. Here, we present the firs...
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| 6 |
04/20/2006 |
16533513 |
Novel two-parameter flow cytometry (MIL4/SSC followed by MIL4/CT7) allows for identification of five fractions of guinea pig leukocytes in peripheral blood and lymphoid organs. |
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Though the guinea pig has been an extremely useful animal model for a variety of diseases, the tools necessary to undertake a full-scale immunological analysis of the guinea pig have been lacking. For...
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| 7 |
01/01/2006 |
17137291 |
Physical interaction of two cancer-testis antigens, MAGE-C1 (CT7) and NY-ESO-1 (CT6). |
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Cancer/testis (CT) antigens are the protein products of germ line-associated genes that are activated in a wide variety of tumors and can elicit autologous cellular and humoral immune responses. CT an...
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| 8 |
12/01/2005 |
16734221 |
Cancer-testis antigen expression in bladder cancer. |
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PURPOSE: To evaluate the potential of cCancer-t/Testis antigens (CTAs) as targets for immunotherapy of bladder cancer, we evaluated the expression of 9 CTA genes or families of genes in normal urothel...
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| 9 |
11/15/2005 |
16299236 |
Cancer-testis genes are coordinately expressed and are markers of poor outcome in non-small cell lung cancer. |
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PURPOSE: Cancer-testis genes mapping to the X chromosome have common expression patterns and show similar responses to modulators of epigenetic mechanisms. We asked whether cancer-testis gene expressi...
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| 10 |
11/04/2005 |
16168960 |
Circadian expression of clock and screening of clock-controlled genes in peripheral lymphocytes of rat. |
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In this paper, the circadian pattern of Clock and genes mediated by the Clock was investigated in peripheral lymphocytes of rats. Circadian rhythms of Clock are found under the regimes of constant dar...
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| 11 |
09/01/2005 |
16438850 |
[The expression of 11 cancer/testis (CT) antigen genes in esophageal carcinoma] |
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OBJECTIVE: To investigate the expression status of 11 different cancer/testis (CT) antigen genes in esophageal carcinoma. METHODS: Esophageal carcinoma tissue and adjacent normal esophageal mucosa tak...
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| 12 |
09/01/2005 |
16083772 |
Biodegradation of nonylphenol in sewage sludge. |
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We investigated the effects of various factors on the aerobic degradation of nonylphenol (NP) in sewage sludge. NP (5 mg/kg) degradation rate constants (k1) calculated were 0.148 and 0.224 day(-1) for...
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| 13 |
07/01/2005 |
15761016 |
The cancer-testis antigens CT7 (MAGE-C1) and MAGE-A3/6 are commonly expressed in multiple myeloma and correlate with plasma-cell proliferation. |
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Multiple myeloma is a malignancy of plasma cells. Vaccine immunotherapy is among the novel therapeutic strategies under investigation for this disease. To identify myeloma-associated antigens as poten...
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| 14 |
06/30/2005 |
16833898 |
Design of density functionals that are broadly accurate for thermochemistry, thermochemical kinetics, and nonbonded interactions. |
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This paper develops two new hybrid meta exchange-correlation functionals for thermochemistry, thermochemical kinetics, and nonbonded interactions. The new functionals are called PW6B95 (6-parameter fu...
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| 15 |
03/10/2005 |
15723723 |
Expression of cancer/testis (CT) antigens in Chinese hepatocellular carcinoma and its correlation with clinical parameters. |
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For investigating the expression of cancer/testis (CT) antigens in patients with hepatocellular carcinoma (HCC) in China, and evaluating the correlations between the expression of these CT antigens an...
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| 16 |
02/01/2005 |
15694019 |
[Cloning and subcellular localization of apr-1--a new gene of tumor specific antigen family] |
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BACKGROUND & OBJECTIVE: apr-1 was cloned by improved polymerase chain reaction (PCR)-based subtractive hybridization from all-trans retinoic acid (ATRA)-induced apoptotic leukemia HL-60 cells in 1999....
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| 17 |
01/01/2005 |
15272278 |
Expression of cancer-testis antigens in endometrial carcinomas using a tissue microarray. |
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Cancer-testis (CT) antigens are expressed in a variety of malignant tumors, but in normal adult tissue, they are only expressed in testicular germ cells. Owing to this tumor-associated expression patt...
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| 18 |
12/01/2004 |
15606517 |
Melanoma or not? Cancer testis antigens may help. |
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BACKGROUND: Cancer testis antigens (CTAs) are expressed in a variety of malignant tumours. No CTA expression is found in normal adult tissues, except in male germ cells and occasionally placenta. To d...
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| 19 |
12/01/2004 |
15515159 |
Expression and significance of cancer testis antigens in primary mucosal melanoma of the head and neck. |
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BACKGROUND.: Cancer testis antigens (CTAs) are T-cell-defined tumor-associated antigens encoded by the genes and gene families such as MAGE, NY-ESO-1, and others. Their expression in a wide variety of...
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| 20 |
03/17/2004 |
15061963 |
[Expression of multiple cancer-testis antigen genes in non-small cell lung cancer treated by chemotherapy prior surgery] |
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OBJECTIVE: To investigate the possibility of utilizing cancer-testi (CT) antigens as targets for immunotherapy of non-small cell lung cancer (NSCLC) with vaccines. METHODS: Tissues from 51 NSCLC patie...
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