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List of genes:

Pubmed

Gene: 

AKAP3 (official gene symbol)

Other symbol: 

AKAP3

CT family: 

CT82 

CT identifier: 

CT82

Aliases from NCBI:

AKAP110 , FSP95 , PRKA3 , SOB1

22 records found.
2 pages with 20 records each.
Show page 2 of 2.
   

ARTICLE DATE PUBMED ID TITLE GENES
1 10/10/2007 17928627 Identification and Characterization of RHOA-Interacting Proteins in Bovine Spermatozoa.
  In somatic cells, RHOA mediates actin dynamics through a GNA13-mediated signaling cascade involving RHO kinase (ROCK), LIM kinase (LIMK), and cofilin. RHOA can be negatively regulated by Protein Kinas...
2 10/01/2007 17551920 A yeast two-hybrid system using Sp17 identified Ropporin as a novel cancer-testis antigen in hematologic malignancies.
  Since most intracellular proteins are expressed with their ligands, ligands of cancer-testis (CT) antigens may also be CT in their distribution. Applying Sperm protein 17 (Sp17) as the bait in a yeast...
3 09/01/2007 17712481 Localization of AKAP4 and tubulin proteins in sperm with reduced motility.
  AIM: To perform screening, related to A-kinase anchoring proteins 4 (AKAP4) and tubulin proteins, in spermatozoa with absent or severely reduced motility in order to detect the status of the fibrous s...
4 12/01/2006 17081177 Transmission electron microscopy, immunocytochemical and fluorescence in situ hybridisation studies in a case of 100% necrozoospermia: case report.
  We present the ultrastructural, functional and chromosomal analyses of sperm from an infertile man with a normal karyotype and 100% necrozoospermia. Tests for microbial infection showed the presence o...
5 09/01/2006 16929165 Expression of cancer-testis antigens as possible targets for antigen-specific immunotherapy in head and neck squamous cell carcinoma.
  Cancer-Testis (CT) antigens are by definition expressed in tumor but not in healthy tissue except testis and might represent ideal targets for antigen-specific immunotherapy. Here, we present the firs...
6 01/01/2006 16177223 AKAP3 selectively binds PDE4A isoforms in bovine spermatozoa.
  Cyclic AMP plays an important role in regulating sperm motility and acrosome reaction through activation of cAMP-dependent protein kinase A (PKA). Phosphodiesterases (PDEs) modulate the levels of cycl...
7 10/01/2005 15980003 Gene deletions in an infertile man with sperm fibrous sheath dysplasia.
  BACKGROUND: Asthenozoospermia may sometimes be related to genetic structural defects of the sperm tail detectable by transmission electron microscopy. Dysplasia of the fibrous sheath (DFS) is a geneti...
8 07/01/2005 16009167 Fluorescence in situ hybridization and molecular studies in infertile men with dysplasia of the fibrous sheath.
  OBJECTIVE: To perform fluorescence in situ hybridization (FISH) and molecular analysis in patients with the genetic sperm defect "dysplasia of the fibrous sheath" (DFS). DESIGN: Retrospective study. S...
9 01/01/2005 15342355 Tyrosine phosphorylation of the a kinase anchoring protein 3 (AKAP3) and soluble adenylate cyclase are involved in the increase of human sperm motility by bicarbonate.
  Mammalian testicular spermatozoa are immotile, thus, to reach the oocyte, they need to acquire swimming ability under the control of different factors acting during the sperm transit through the epidi...
10 07/16/2004 15257753 Association of sperm protein 17 with A-kinase anchoring protein 3 in flagella.
  BACKGROUND: Sperm protein 17 (Sp17) is a three-domain protein that contains: 1) a highly conserved N-terminal domain that is 45% identical to the human type II alpha regulatory subunit (RII alpha) of ...
11 03/01/2004 14996943 Increased phosphorylation of AKAP by inhibition of phosphatidylinositol 3-kinase enhances human sperm motility through tail recruitment of protein kinase A.
  Sperm motility is regulated by a complex balance between kinases and phosphatases. Among them, phosphatidylinositol 3-kinase (PI 3-kinase) has been recently suggested to negatively regulate sperm moti...
12 01/01/2004 14618620 A-kinase anchoring protein 3 messenger RNA expression in ovarian cancer and its implication on prognosis.
  A-kinase anchoring protein 3 (AKAP3) is a sperm protein and its expression appears to be restricted to the testis in normal adult tissues. We investigated AKAP3 mRNA expression in 20 normal ovaries an...
13 06/01/2003 12606363 A-kinase anchoring protein 4 binding proteins in the fibrous sheath of the sperm flagellum.
  The fibrous sheath is a unique cytoskeletal structure located in the principal piece of the sperm flagellum and is constructed of two longitudinal columns connected by closely spaced circumferential r...
14 05/01/2003 12887088 How do sperm swim? Molecular mechanisms underlying sperm motility.
  Motility is a characteristic function of the male gamete, which allows spermatozoa to actively reach and penetrate the female gamete in organisms with internal and external fertilization. Sperm motili...
15 05/01/2003 12672126 Fibrous sheath of mammalian spermatozoa.
  The fibrous sheath is a unique cytoskeletal structure surrounding the axoneme and outer dense fibers and defines the extent of the principal piece region of the sperm flagellum. It consists of two lon...
16 02/01/2003 12653254 2P1, a novel male mouse cDNA specifically expressed during meiosis.
  We screened a mouse germinal cell expression library with a probe derived from Sob1, a human testis-specific cDNA, and identified 2P1, a new mouse cDNA. A database search revealed that 2P1 was 91% ide...
17 10/30/2001 11696326 Interaction of heterotrimeric G13 protein with an A-kinase-anchoring protein 110 (AKAP110) mediates cAMP-independent PKA activation.
  Heterotrimeric G proteins and protein kinase A (PKA) are two important transmitters that transfer signals from a wide variety of cell surface receptors to generate physiological responses. The establi...
18 05/18/2001 11278869 Identification of sperm-specific proteins that interact with A-kinase anchoring proteins in a manner similar to the type II regulatory subunit of PKA.
  The cAMP-dependent protein kinase (PKA) is targeted to specific subcellular compartments through its interaction with A-kinase anchoring proteins (AKAPs). AKAPs contain an amphipathic helix domain tha...
19 03/01/2001 11229805 Molecular genetic analysis of two human sperm fibrous sheath proteins, AKAP4 and AKAP3, in men with dysplasia of the fibrous sheath.
  Dysplasia of the fibrous sheath (DFS) is characterized by male infertility, asthenozoospermia, and morphologically abnormal flagella that possess a severely malformed fibrous sheath. In many cases, DF...
20 11/01/1999 10529264 FSP95, a testis-specific 95-kilodalton fibrous sheath antigen that undergoes tyrosine phosphorylation in capacitated human spermatozoa.
  Protein tyrosine phosphorylation has been associated with both capacitation and motility of mammalian sperm. During capacitation, human spermatozoa undergo tyrosine phosphorylation of a characteristic...