mRNA expression
Gene:
MAGEA1 (official gene symbol)Other symbol:
MAGEA1CT family:
CT1CT identifier:
CT1.1Aliases from NCBI:
MAGE1 , MGC9326Gene expression pattern ? : Testis-restricted
High-throughput data (expression in cancer samples)
SAGE(short, 10 nt tags) Show
SAGE(long, 17 nt tags) Show
MPSS (short, 13 nt tags) Show
EST Show
Published data of mRNA expression in normal tissues
Show| Tissue | Methodology | PMID |
|---|---|---|
| Pancreas | RT-PCR | 14738373 |
| Testis | RT-PCR | 14738373 |
| Testis | RT-PCR | 7927540 |
| Testis | RT-PCR | 8276455 |
| Testis | Oligonucleotide microarray | 11751535 |
| Ovary | RT-PCR | 9743307 |
| Bone marrow | Nested RT-PCR | 15781633 |
| Mesenchymal stem cells | Nested RT-PCR | 15781633 |
| Skin (wound healing) | Northern blot | 8050815 |
| Acute sigma diverticulitis | RT-PCR | 15142679 |
Published data of mRNA expression in neoplasias
Hematologic malignacies Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Myeloma |
Primary tumor | 11/21 (52%) | RT-PCR | 10741395 |
| Myeloma |
0/9 (0%)(stage I) | RT-PCR | 10438702 | |
| Myeloma |
8/26 (31%)(stage III) | RT-PCR | ||
| Myeloma |
0/2 (0%(stage II) | RT-PCR | ||
| Monoclonal gammopathy of undetermined significance (MGUS) |
3/6 (50%) | RT-PCR | 15761016 | |
| Myeloma |
2/10 (20%) | RT-PCR | ||
| Myeloma |
11/39 (31%) | RT-PCR | 18237105 | |
| Adult T-cell leukemia/lymphoma (ATLL) |
3/34 (9%) | RT-PCR | 22323448 |
Bladder cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Transitional cell carcinoma |
58/102 (57%) | RT-PCR | 21396841 |
Brain cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Glioblastoma |
17/43 (39.5%) | RT-PCR | 15256472 | |
| Astrocytoma |
1/3 (33%) | RT-PCR | 9176405 | |
| Glioblastoma |
8/21 (38%) | RT-PCR | ||
| Meningioma |
2/3 (67%) | RT-PCR | ||
| Oligodendroglioma |
1/1 (100%) | RT-PCR | ||
| Ependymoma (Pediatric) |
0/14 (0%) | RT-PCR | 10037183 | |
| Glioblastoma multiforme |
0/20 (0%) | RT-PCR | ||
| Glioblastoma multiforme (Pediatric) |
0/9 (0%) | RT-PCR | ||
| Medulloblastoma (Pediatric) |
1/11 (9%) | qRT-PCR | 18398575 | |
| Glioma |
2/30 (7%) | RT-PCR | 18240144 | |
| Medulloblastomas |
4/25 (16%) | RT-PCR | 18426187 | |
| Glioma |
7/45 (16%) | RT-PCR | 22534618 | |
| Meningioma |
0/26 (0%) | RT-PCR |
Head & Neck cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Squamous cell carcinoma |
Primary tumor | 17/57 (30%) | RT-PCR | 20715104 |
| Oral squamous cell carcinoma |
2/20 (10%) | RT-PCR | 22447174 |
Hepatobiliary cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Hepatocellular carcinoma |
7/10 (70%)(Well differentiated) | RT-PCR | 10782910 | |
| Hepatocellular carcinoma |
� (50%)(Poorly differentiated) | RT-PCR | ||
| Hepatocellular carcinoma |
14/20 (70%)(Mod differentiated) | RT-PCR | ||
| Hepatocellular carcinoma |
79/105 (75%) | RT-PCR | 15237429 | |
| Hepatocellular carcinoma |
51/73 (69.9%) | RT-PCR | 15723723 | |
| Hepatocellular carcinoma |
4/21 (19%) | RT-PCR | 12747756 | |
| Hepatocellular carcinoma |
5/8 (62%)(Well differentiated) | RT-PCR | 10576668 | |
| Hepatocellular carcinoma |
� (50%)(Poorly differentiated) | RT-PCR | ||
| Hepatocellular carcinoma |
15/17 (88%)(Mod differentiated) | RT-PCR | ||
| Hepatocellular carcinoma |
16/20 (80%) | RT-PCR | 8938177 | |
| Hepatocellular carcinoma |
14/22 (65%) | RT-PCR | 10189127 | |
| Hepatocellular carcinoma |
27/45 (60%) | RT-PCR | 10488416 | |
| Hepatocellular carcinoma |
23/50 (46%) | RT-PCR | 10220740 | |
| Hepatocellular carcinoma |
27/45 (60%) | RT-PCR | 10592101 | |
| Hepatocellular carcinoma |
0/4 (0%)(Well differentiated) | RT-PCR | 10568832 | |
| Hepatocellular carcinoma |
18/56 (32%)(Mod or poorly differentiated) | RT-PCR | ||
| Hepatocellular carcinoma |
32/45 (71.1%) | RT-PCR | 11776148 | |
| Hepatocellular carcinoma |
Tumor | 21/30 (70%) | RT-PCR | 11857021 |
| Hepatocellular carcinoma |
Blood sample | 13/30 (43.3%) | RT-PCR | |
| Biliary tract carcinoma |
5/32 (16%) | RT-PCR | 10873083 | |
| Hepatocellular carcinoma |
35/47 (74%) | RT-PCR | 15059354 | |
| Hepatocellular carcinoma |
32/45 (71%) | RT-PCR | 11715455 | |
| Hepatocellular carcinoma |
Blood sample | 34/90 (38%) | RT-PCR | 20731022 |
| Hepatocellular carcinoma |
Tumor | 67/90 (74%) | RT-PCR |
Lung cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Adenocarcinoma |
3/22 (14%) | RT-PCR | 14512184 | |
| Adenosquamous carcinoma |
0/1 (0%) | RT-PCR | ||
| Large cell carcinoma |
1/6 (17%) | RT-PCR | ||
| Small cell lung carcinoma |
0/4 (0%) | RT-PCR | ||
| Squamous cell carcinoma |
8/13 (62%) | RT-PCR | ||
| Adenocarcinoma |
82/200 (41%) | RT-PCR | 16299236 | |
| Bronchioloalveolar / adenobronchioloalveolar carcinoma |
33/98 (34%) | RT-PCR | ||
| Squamous cell carcinoma |
62/87 (71%) | RT-PCR | ||
| Adenocarcinoma |
4/35 (11%) | RT-PCR | 7622303 | |
| Large cell carcinoma |
0/1 (0%) | RT-PCR | ||
| Small cell lung carcinoma |
0/3 (0%) | RT-PCR | ||
| Squamous cell carcinoma |
2/14 (14%) | RT-PCR | ||
| Lung carcinoma |
3/12 (25%) | Nested RT-PCR | 12133624 | |
| Adenocarcinoma |
8/18 (44%) | RT-PCR | 8119772 | |
| Large cell carcinoma |
0/2 (0%) | RT-PCR | ||
| Small cell lung carcinoma |
1/3 (33%) | RT-PCR | ||
| Squamous cell carcinoma |
8/26 (31%) | RT-PCR | ||
| Adenocarcinoma |
3/25 (12%) | RT-PCR | 9486785 | |
| Adenosquamous carcinoma |
0/2 (0%) | RT-PCR | ||
| Squamous cell carcinoma |
6/16 (37.5%) | RT-PCR | ||
| Non small cell lung carcinoma |
Primary tumor | 14/20 (70%) | RT-PCR | 11691819 |
| Non small cell lung carcinoma |
Bronchial brush specimens from former smokers | 7/20 (35%) | RT-PCR | |
| Non small cell lung carcinoma |
Adjacent normal tissue | 13/20 (65%) | RT-PCR | |
| Adenocarcinoma |
7/30 (23%) | RT-PCR | 9711530 | |
| Squamous cell carcinoma |
11/20 (55%) | RT-PCR | ||
| Adenocarcinoma |
3/29 (10%) | RT-PCR | 22138038 | |
| Squamous cell carcinoma |
4/29 (14%) | RT-PCR |
Melanocytic lesion Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Melanoma |
Metastatic tumor | 9/16 (56%) | RT-PCR | 9650552 |
| Melanoma |
9/10 (90%) | Nested RT-PCR | 12190937 | |
| "In situ" melanoma |
0/3 (0%) | RT-PCR | 10215777 | |
| Benign melanocytic nevus |
0/10 (0%) | RT-PCR | ||
| Dysplastic nevus |
0/14 (0%) | RT-PCR | ||
| Melanoma |
Primary tumor | 0/4 (0%) | RT-PCR | |
| Melanoma |
Metastatic tumor | 1/3 (33%) | RT-PCR | |
| Benign nevocellular nevus |
0/12 (0%) | RT-PCR | 7591235 | |
| Dysplastic nevus |
0/4 (0%) | RT-PCR | ||
| Melanoma |
Metastatic tumor | 70/145 (48%) | RT-PCR | |
| Melanoma |
Primary tumor | 16/100 (16%) | RT-PCR | |
| Ocular melanoma |
Primary tumor | 1/1 (100%) | RT-PCR | 9247253 |
| Ocular melanoma |
Metastatic tumor | � (75%) | RT-PCR | |
| Melanoma |
5/12 (42%) | RT-PCR | 9176405 | |
| Melanoma |
8/23 (35%) | RT-PCR | 9766577 | |
| Melanoma |
15/47 (32%) | RT-PCR | 10890380 | |
| Melanoma |
83/202 (41%) | RT-PCR | 19326132 |
OTHER CANCER Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Neuroblastoma |
17/47 (36%) | RT-PCR | 18820946 |
Ovarian cancer Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Mucinous ovarian carcinoma |
Peritoneal fluid | 0/5 (0%) | RT-PCR | 12115308 |
| Papillary ovarian carcinoma |
Peritoneal fluid | 0/11 (0%) | RT-PCR | |
| Serous-papillary ovarian carcinoma |
Peritoneal fluid | 2/11 (18%) | RT-PCR | |
| Ovarian carcinoma |
Benign lesion | 11/25 (44%) | RT-PCR | 9743307 |
| Ovarian carcinoma |
Primary tumor | 15/27 (55%) | RT-PCR | |
| Dermatoid cyst with malignant transformation |
0/12 (0%) | RT-PCR | 8550240 | |
| Endometrioid carcinoma |
2/15 (13.3%) | RT-PCR | ||
| Granulosa cell tumor |
0/4 (0%) | RT-PCR | ||
| Mucinous adenocarcinoma |
0/16 (0%) | RT-PCR | ||
| Ovarian carcinoma |
Metastatic tumor | 0/9 (0%) | RT-PCR | |
| Ovarian fibrosarcoma |
1/1 (100%) | RT-PCR | ||
| Serous ovarian adenocarcinoma |
8/19 (42%) | RT-PCR | ||
| Transitional cell carcinoma |
1/12 (8.3%) | RT-PCR | ||
| Yolk-sac tumor |
0/4 (0%) | RT-PCR |
Sarcoma Show
| Tumor Subtype | Sample type | Frequency | Methodology | PMID |
|---|---|---|---|---|
| Osteosarcoma |
28/28 (100%) | RT-PCR | 22009167 |
Published data of mRNA expression in Cell Lines
Show| Origin tissue | Cell Line ID | Frequency | Methodology | PMID |
|---|---|---|---|---|
| 2 | ||||
| Bladder carcinoma | LB905-BLC | Oligonucleotide microarray | 11751535 | |
| Brain tumor- Glioblastoma | LAN-2 SK-N-DZ SK-N-F1 SK-N-BE |
4/15 (27%) | RT-PCR | 8509230 |
| Breast carcinoma | HBL-HX Hs578T |
2/4 (50%) | RT-PCR | 8416750 |
| Breast carcinoma | HM InLa KS SkBr3 T47D |
5/13 (38%) | RT-PCR | 12836015 |
| Colon carcinoma | MZ-CO-2 | RT-PCR | 7927540 | |
| Colorectal carcinoma | SNU-175 SNU-283 SNU-407 SNU-503 SNU-769A SNU-769B SNU-1033 SNU-1047 SNU-1197 SNU-C2A SNU-C4 COLO320 HCT-116 HT-29 Lovo LS174T NCI-H716 SW403 SW480 WiDR |
19/32 (59%) | RT-PCR | 17007017 |
| Colorectal carcinoma | VMRC-MELG LoVo WiDr Colo205 |
4/8 (50%) | RT-PCR | 8757382 |
| Gastrict carcinoma | NUGC3 NS8 MKN74 MKN7 MKN28 KATOIII |
6/9 (67%) | RT-PCR | 10446460 |
| Gastrict carcinoma | MKN1 MKN7 MKN28 MKN74 KATO-III TSG11 ECC12 |
7/10 (70%) | RT-PCR | 14970862 |
| Glioma | 1/13 (8%) | RT-PCR | 22534618 | |
| Hepatocellular carcinoma | SMMC-7721 BEL-74-2 |
2/3 (67%) | RT-PCR | 14607688 |
| Leukemia | K562 HL60 HEL |
RT-PCR | 11681419 | |
| Lung carcinoma | H209 H345 H510 LB11 LB37 |
Northern blot | 1840703 | |
| Lung carcinoma- NSCLC | NCI-H2023 NCI-H157 NCI-H460 NCI-H820 NCI-H1264 NCI-H1299 NCI-H1623 NCI-H1693 NCI-H944 |
9 /31 (29%) | RT-PCR | 11551413 |
| Lung carcinoma- SCLC | LBll | RT-PCR | 7927540 | |
| Lung carcinoma- SCLC | OC1 | Oligonucleotide microarray | 11751535 | |
| Medullary thyroid carcinoma | TT | Northern blot | 1840703 | |
| Melanoma | LB1751-MEL LB373-MEL AVL3-MEL |
Oligonucleotide microarray | 11751535 | |
| Melanoma | 397-mel 397-R4-mel 501-mel 553-mel 586-mel 697-mel 836-mel 938-mel MZ2-mel-43 |
9/17 (53%) | RT-PCR | 8416750 |
| Melanoma | MZ2.MEL3.0 LB34-MEL M110221-MEL M113443-MEL SK33-MEL SK23-MEL LB17-MEL LB33-MEL MI4024-MEL MZ3-MEL MZ5-MEL |
Northern blot | 1840703 | |
| Melanoma | WM115-A WM1972-A WM1976-A WM3130-A |
4/4 (100%) | RT-PCR | 18205182 |
| Melanoma | MI10221 MZ2-MEL3.0 |
RT-PCR | 7927540 | |
| Melanoma | MZ2-MEL MZ2-MEL.61D LY1-MEL MI-10221-MEL LY2-MEL LB34-MEL MI-13441-MEL LB33-MEL LB73-MEL |
9/16 (56%) | RT-PCR | 8113684 |
| Melanoma | MI10221 MZ2-MEL3.0 |
RT-PCR | 7927540 | |
| Melanoma | UKRV-Mel-02 WM98.1 UKRV-Mel-14 UKRV-Mel-20 UKRV-Mel-06 UKRV-Mel-21 UKRV-Mel-31 UKRV-Mel-27 Ma-Mel-13 |
20/24 (83%) | Nested RT-PCR | 12190937 |
| Melanoma | 553-B 586-M 836-M 1195-M 1274-M 1359-M 1390-M |
7/38 (18%) | qRT-PCR | 10842196 |
| Melanoma | Sk-Mel-37 Sk-Mel-28 Sk-Mel-24 Malme-3M |
4/5 (80%) | RT-PCR | 18395366 |
| Melanoma | Ma-Mel-11 Ma-Mel-13 Ma-Mel-18 Ma-Mel-22 Ma-Mel-33 Ma-Mel-36 Ma-Mel-37 UKRV-Mel-06 UKRV-Mel-10 UKRV-M |
12/15 (80%) | RT-PCR | 12932233 |
| Melanoma stem cells (MSC) | WM115-NA WM1972-NA WM1976-NA WM3130-NA |
4/4 (100%) | RT-PCR | 18205182 |
| Myeloma | BCN MDN SBN XG1 XG2 XG6 XG7 AMO-1 Karpas 620 L363 NCI-H929 0PM2 RPMI-8226 U266 |
14/17 (82%) | RT-PCR | 10741395 |
| Neuroblastoma | LN-215 LN-428 LN-464 LN-229 LN-18 LN-235 |
6/10 (60%) | RT-PCR | 8509230 |
| Ovarian carcinoma | FraW KlHe |
2/6 (33%) | RT-PCR | 12836015 |
| Ovarian carcinoma | OVK-18 ES-2 |
2/14 (14%) | qRT-PCR | 11985796 |
| Sarcoma | SW872 Saos2 HT-1080 |
3/8 (37%) | RT-PCR | 15298487 |
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