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List of genes:

Pubmed

Gene: 

TPTE (official gene symbol)

Other symbol: 

TPTE

CT family: 

CT44 

CT identifier: 

CT44

Aliases from NCBI:

PTEN2

16 records found.

ARTICLE DATE PUBMED ID TITLE GENES
1 01/18/2008 17977648 Genome-wide expression profiling reveals transcriptomic variation and perturbed gene networks in androgen-dependent and androgen-independent prostate cancer cells.
  Previously, we have developed a unique in vitro LNCaP cell model, which includes androgen-dependent (LNCaP-C33), androgen-independent (LNCaP-C81) and an intermediate phenotype (LNCaP-C51) cell lines r...
2 12/12/2007 18074101 Gene dosage change of TPTE and BAGE2 and breakpoint analysis in Robertsonian Down syndrome.
  Only 4% of Down syndrome (DS) cases have a Robertsonian translocation (ROB). The aim of this study was to define the possible breakage area in 21p where ROB occurs. We prospectively and consecutively ...
3 01/23/2007 17240336 PtdIns(3,4,5)P(3)-dependent and -independent roles for PTEN in the control of cell migration.
  BACKGROUND: Phosphatase and tensin homolog (PTEN) mediates many of its effects on proliferation, growth, survival, and migration through its PtdIns(3,4,5)P(3) lipid phosphatase activity, suppressing p...
4 09/01/2006 16929165 Expression of cancer-testis antigens as possible targets for antigen-specific immunotherapy in head and neck squamous cell carcinoma.
  Cancer-Testis (CT) antigens are by definition expressed in tumor but not in healthy tissue except testis and might represent ideal targets for antigen-specific immunotherapy. Here, we present the firs...
5 05/01/2006 16575538 Predicting which children are at risk for ependymoma relapse.
  Ependymomas account for 6-12% of all pediatric intracranial tumors. Despite complete resection and radiation, about 50% of patients relapse and have subsequent dismal prognoses. As no clinical finding...
6 12/01/2005 16373702 Transcript profiling in peripheral T-cell lymphoma, not otherwise specified, and diffuse large B-cell lymphoma identifies distinct tumor profile signatures.
  To glean biological differences and similarities of peripheral T-cell lymphoma-not otherwise specified [PTCL-NOS] to diffuse large B-cell lymphoma (DLBCL), a transcriptosome analysis was done on five ...
7 08/12/2005 15951562 Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-associated serine/threonine kinases.
  The tumor suppressor phosphatase PTEN is a key regulator of cell growth and apoptosis that interacts with PDZ domains from regulatory proteins, including MAGI-1/2/3, hDlg, and MAST205. Here we identif...
8 04/01/2004 15046604 Acute regulation of the tumour suppressor phosphatase, PTEN, by anionic lipids and reactive oxygen species.
  PTEN (phosphatase and tensin homologue deleted on chromosome 10) is a member of the protein tyrosine phosphatase family that is structurally adapted to facilitate the metabolism of 3-phosphoinositide ...
9 12/24/2003 14659893 The TPTE gene family: cellular expression, subcellular localization and alternative splicing.
  The human TPTE (Transmembrane Phosphatase with TEnsin homology) gene family encodes a PTEN-related tyrosine phosphatase with four potential transmembrane domains. Chromosomal mapping revealed multiple...
10 07/21/2003 12865919 Identification of two novel CT antigens and their capacity to elicit antibody response in hepatocellular carcinoma patients.
  FATE and TPTE genes were originally reported to be specifically expressed in the adult testis. We searched for the databases of Unigene and serial analysis of gene expression (SAGE) implying that thes...
11 07/17/2003 12909339 Juxtacentromeric region of human chromosome 21: a boundary between centromeric heterochromatin and euchromatic chromosome arms.
  We have analysed the genomic structure and transcriptional activity of a 2.3-Mb genomic sequence in the juxtacentromeric region of human chromosome 21. Our work shows that this region comprises two di...
12 12/01/2001 11810268 The murine orthologue of the Golgi-localized TPTE protein provides clues to the evolutionary history of the human TPTE gene family.
  The human TPTE gene encodes a testis-specific protein that contains four potential transmembrane domains and a protein tyrosine phosphatase motif, and shows homology to the tumor suppressor PTEN/MMAC1...
13 12/01/2001 11716755 TPIP: a novel phosphoinositide 3-phosphatase.
  The PTEN (phosphatase and tensin homologue deleted on chromosome 10) tumour suppressor is a phosphatidylinositol 3,4,5-trisphosphate [PtdIns(3,4,5)P(3)] 3-phosphatase that plays a critical role in reg...
14 08/01/2000 11030409 Genomic structure of a copy of the human TPTE gene which encompasses 87 kb on the short arm of chromosome 21.
  The testis-expressed human TPTE is a putative transmembrane tyrosine phosphatase, probably involved in signal transduction pathways of the endocrine and/or the spermatogenetic function of the testis. ...
15 11/01/1999 10598804 A testis-specific gene, TPTE, encodes a putative transmembrane tyrosine phosphatase and maps to the pericentromeric region of human chromosomes 21 and 13, and to chromosomes 15, 22, and Y.
  To contribute to the creation of a transcription map of human chromosome 21 (HC21) and to the identification of genes that may be involved in the pathogenesis of Down syndrome, exon trapping was perfo...
16 09/24/1998 9794233 Mutation analysis of the PTEN/MMAC1 gene in lung cancer.
  We studied PTEN/MMAC1, a newly discovered candidate tumor suppressor gene at 10q23.3, for mutations in lung cancer. One hundred and thirty-six lung cancer cell line DNAs (66 small cell lung cancers, S...