| 1 | 09/01/2007 | 17553591 | Chromosomal aberrations of malignant pleural effusions of lung adenocarcinoma: different cytogenetic changes are correlated with genders and smoking habits. |  | 
 
                  |  | Chromosomal aberrations of malignant cells from pleural effusions of 31 cases of lung adenocarcinoma were analyzed. Pooled CGH results showed frequent amplifications on chromosome arms 1p (22.6%), 1q ... 
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                  | 2 | 09/01/2006 | 16929165 | Expression of cancer-testis antigens as possible targets for antigen-specific immunotherapy in head and neck squamous cell carcinoma. |  | 
 
                  |  | Cancer-Testis (CT) antigens are by definition expressed in tumor but not in healthy tissue except testis and might represent ideal targets for antigen-specific immunotherapy. Here, we present the firs... 
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                  | 3 | 08/01/2006 | 17178662 | Increased serum lactate dehydrogenase isoenzymes in Ph-negative chronic myeloproliferative diseases: a metabolic adaptation? |  | 
 
                  |  | We evaluated the significance of lactate dehydrogenase (LDH) isoenzymes in chronic myeloproliferative disorders (CMDs) by studying LDH isoenzymes in the serum of patients with secondary polycythemia (... 
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                  | 4 | 07/01/2006 | 16582413 | Testis-specific lactate dehydrogenase (LDH-C4; Ldh3) in murine oocytes and preimplantation embryos. |  | 
 
                  |  | LDH-C(4) (Ldh3) is a member of the lactate dehydrogenase family of isozymes that catalyze the terminal reaction in the glycolytic pathway. In mammals, 3 genes, ldha, ldhb, and Ldhc, encode the subunit... 
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                  | 5 | 05/15/2006 | 16353146 | Expression of multiple epigenetically regulated cancer/germline genes in nonsmall cell lung cancer. |  | 
 
                  |  | Cancer/germline (CG) antigens represent promising targets for widely applicable mono- and multiantigen cancer vaccines for nonsmall cell lung cancer (NSCLC). Since little is known about their composit... 
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                  | 6 | 01/01/2006 | 16397242 | Genomic and expression profiling of human spermatocytic seminomas: primary spermatocyte as tumorigenic precursor and DMRT1 as candidate chromosome 9 gene. |  | 
 
                  |  | Spermatocytic seminomas are solid tumors found solely in the testis of predominantly elderly individuals. We investigated these tumors using a genome-wide analysis for structural and numerical chromos... 
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                  | 7 | 04/01/2005 | 15966667 | [Serum lactate dehydrogenase and its isoenzymes in nasopharyngeal carcinoma in Tunisia] |  | 
 
                  |  | Our prospective study interested 41 patients, from 13 to 70 years old, and present a nasopharyngeal carcinoma confirmed histologically, during the period going from September 1999 to March 2000, and 4... 
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                  | 8 | 05/15/2004 | 15133854 | Establishment and characterization of human hepatocellular carcinoma cell line FHCC-98. |  | 
 
                  |  | AIM: To establish a novel human hepatocellular carcinoma (HCC) cell line FHCC-98 from HCC tissue and to provide a suitable model for studying HCC occurrence, progress and metastasis. METHODS: Serially... 
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                  | 9 | 05/01/2004 | 14985855 | A spermatogenesis-related gene expression profile in human spermatozoa and its potential clinical applications. |  | 
 
                  |  | Spermatogenesis is an essential stage in the human reproductive process. In a previously study aiming to determine which genes might be involved in spermatogenesis, we compared the gene expression pro... 
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                  | 10 | 11/01/2003 | 14581519 | Abundance of repetitive sequence elements in the mouse testis-specific lactate dehydrogenase-C gene. |  | 
 
                  |  | We have cloned and sequenced the entire mouse ldhc gene and mapped it physically in relation to the somatic ldha gene. The 2 genes were found to be oriented in head-to-tail fashion with about a 6-kilo... 
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                  | 11 | 11/15/2002 | 12438276 | Multiple splice variants of lactate dehydrogenase C selectively expressed in human cancer. |  | 
 
                  |  | We applied a combined data mining and experimental validation Approach for the discovery of germ cell-specific genes aberrantly expressed in cancer. Six of 21 genes with confirmed germ cell specificit... 
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                  | 12 | 09/21/2001 | 11447215 | ldhc expression in non-germ cell nuclei is repressed by NF-I binding. |  | 
 
                  |  | Developmental and testis-specific expression of the mouse lactate dehydrogenase C (mldhc) gene requires mechanisms for activation in germ cells and repression in somatic cells. Promoter activity restr... 
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                  | 13 | 01/25/2000 | 10721707 | cDNA cloning of pig testicular lactate dehydrogenase-C, thermal stability of the expressed enzyme, and polymorphism among strains. |  | 
 
                  |  | Pig testicular lactate dehydrogenase-C (LDHC) cDNA was cloned and sequenced. The deduced sequence of 332 amino acids from pig LDHC shows 73% and 67% identity with that of pig LDHA (muscle) and LDHB (h... 
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                  | 14 | 11/20/1998 | 9813024 | Transgenic mice demonstrate a testis-specific promoter for lactate dehydrogenase, LDHC. |  | 
 
                  |  | The mammalian genome encodes a family of lactate dehydrogenase (LDH) isozymes. Two of these, ldha and ldhb, are expressed ubiquitously. The ldhc gene is active only in the germinal epithelium during s... 
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                  | 15 | 09/01/1998 | 9723174 | Human testis-specific lactate dehydrogenase-C promoter drives overexpression of mouse lactate dehydrogenase-1 cDNA in testes of transgenic mice. |  | 
 
                  |  | The three isozymes of lactate dehydrogenase, each encoded by a separate gene, are developmentally regulated and differentially expressed in tissue-specific patterns. The lactate dehydrogenase-C (LDHC,... 
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                  | 16 | 05/01/1997 | 9222698 | The characteristics of hepatocellular carcinoma with a high level of serum lactic dehydrogenase: a case report. |  | 
 
                  |  | Hepatocellular carcinoma (HCC) remains one of the most important malignancies in Japan (1, 2). Lactic dehydrogenase (LDH), which is a glycolyticenzyme, and exists in various types of human tissue and ... 
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                  | 17 | 02/01/1993 | 8439765 | Changes in lactate dehydrogenase isoenzyme pattern in patients with tumors of the central nervous system. |  | 
 
                  |  | Lactate dehydrogenase (LDH) isoenzymes were studied in biopsy samples obtained from 100 benign and malignant brain tumors. Diagnosis was confirmed by histopathology. It is observed that all tumors inv... 
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                  | 18 | 07/01/1989 | 2596827 | Regional localization of the sperm-specific lactate dehydrogenase, LDHC, gene on human chromosome 11. |  | 
 
                  |  | A cDNA clone complementary to the mRNA encoding the sperm-specific lactate dehydrogenase, LDHC, has been used to map the LDHC locus to the short arm of human chromosome 11. In situ hybridization data ... 
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                  | 19 | 09/01/1988 | 3175768 | Assignment of human gene encoding testis-specific lactate dehydrogenase C to chromosome 11, region p14.3-p15.5. |  | 
 
                  |  | The human gene coding for lactate dehydrogenase C (LDHC), a testis-specific isozyme, has been assigned to a refined region of chromosome 11, p14.3-p15.5, in which the lactate dehydrogenase A gene (LDH... 
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                  | 20 | 01/01/1988 | 3180843 | Mapping of human lactate dehydrogenase-A, -B, and -C genes and their related sequences: the gene for LDHC is located with that for LDHA on chromosome 11. |  | 
 
                  |  | Human testis-specific lactate dehydrogenase-C (LDHC) gene-related sequences are located with the LDHA gene on chromosome 11. The LDHB gene is on chromosome 12. Chromosomes 1, 2, 4, 9, and 10 appear to... 
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